An explorative review on advanced approaches to overcome bacterial resistance by curbing bacterial biofilm formation
F Mohamad, RR Alzahrani, A Alsaadi… - Infection and Drug …, 2023 - Taylor & Francis
The continuous emergence of multidrug-resistant pathogens evoked the development of
innovative approaches targeting virulence factors unique to their pathogenic cascade …
innovative approaches targeting virulence factors unique to their pathogenic cascade …
Understanding and targeting resistance mechanisms in cancer
Resistance to cancer therapies has been a commonly observed phenomenon in clinical
practice, which is one of the major causes of treatment failure and poor patient survival. The …
practice, which is one of the major causes of treatment failure and poor patient survival. The …
A comprehensive review on genomics, systems biology and structural biology approaches for combating antimicrobial resistance in ESKAPE pathogens …
In recent decades, antimicrobial resistance has been augmented as a global concern to
public health owing to the global spread of multidrug-resistant strains from different ESKAPE …
public health owing to the global spread of multidrug-resistant strains from different ESKAPE …
In silico methods for identification of potential therapeutic targets
X Zhang, F Wu, N Yang, X Zhan, J Liao, S Mai… - Interdisciplinary …, 2022 - Springer
At the initial stage of drug discovery, identifying novel targets with maximal efficacy and
minimal side effects can improve the success rate and portfolio value of drug discovery …
minimal side effects can improve the success rate and portfolio value of drug discovery …
In silico structure evaluation of BAG3 and elucidating its association with bacterial infections through protein–protein and host‐pathogen interaction analysis
BAG3, a co‐chaperone protein with a Bcl‐2‐associated athanogene (BAG) domain, has
diverse functionalities in protein‐folding, apoptosis, inflammation, and cell cycle regulatory …
diverse functionalities in protein‐folding, apoptosis, inflammation, and cell cycle regulatory …
The Art of War with Pseudomonas aeruginosa: Targeting Mex Efflux Pumps Directly to Strategically Enhance Antipseudomonal Drug Efficacy
Pseudomonas aeruginosa (P. aeruginosa) poses a grave clinical challenge due to its
multidrug resistance (MDR) phenotype, leading to severe and life-threatening infections …
multidrug resistance (MDR) phenotype, leading to severe and life-threatening infections …
Gene interaction network studies to decipher the multi-drug resistance mechanism in Salmonella enterica serovar Typhi CT18 reveal potential drug targets
Salmonella enterica subsp. enterica serovar Typhi, a human enteric pathogen causing
typhoid fever, developed resistance to multiple antibiotics over the years. The current study …
typhoid fever, developed resistance to multiple antibiotics over the years. The current study …
Low-Fouling and Antibacterial Polymer Brushes via Surface-Initiated Polymerization of a Mixed Zwitterionic and Cationic Monomer
N Burmeister, E Zorn, L Preuss, D Timm, N Scharnagl… - Langmuir, 2023 - ACS Publications
The use of surface-grafted polymer brushes with combined low-fouling and antibacterial
functionality is an attractive strategy to fight biofilm formation. This report describes a new …
functionality is an attractive strategy to fight biofilm formation. This report describes a new …
The revaluation of plant-derived terpenes to fight antibiotic-resistant infections
F Cappiello, MR Loffredo, C Del Plato, S Cammarone… - Antibiotics, 2020 - mdpi.com
The discovery of antibiotics has revolutionized the medicine and treatment of microbial
infections. However, the current scenario has highlighted the difficulties in marketing new …
infections. However, the current scenario has highlighted the difficulties in marketing new …
Oil-contaminated sites act as high-risk pathogen reservoirs previously overlooked in coastal zones
X Lin, J Ma, Z Zhou, B Qiao, Y Li, W Zheng, Y Tian - Water Research, 2023 - Elsevier
In addition to the organic pollutants and disturbance to the microbial, plant and animal
systems, oil contamination can also enrich opportunistic pathogens. But little is known about …
systems, oil contamination can also enrich opportunistic pathogens. But little is known about …