Simple Summary Over the last decade, immune checkpoint inhibitors (ICIs) targeting
programmed death 1 (PD-1), programmed death-ligand 1 (PD-L1), and cytotoxic T …

Introduction: Biliary tract cancer (BTC) is a heterogeneous group of aggressive malignancies
comprising intrahepatic cholangiocarcinoma, extrahepatic cholangiocarcinoma, gallbladder …

ABSTRACT Introduction Biliary tract cancers (BTCs) are poor prognosis malignancies
usually classified in intrahepatic cholangiocarcinoma (iCCA), extrahepatic …

Peripheral blood of cancer patients “physiologically” presents cells and cellular components
deriving from primary or metastatic sites, including circulating tumor cells (CTCs), circulating …

Cholangiocarcinoma (CCA) represents the second‐most common primary liver malignancy
after HCC and has risen in incidence globally in the past decades. Intrahepatic …

Introduction: Unfortunately, potentially curative surgical resection is possible in
approximately the 25% of biliary tract cancer (BTC) patients at diagnosis, and even following …

Simple Summary Intrahepatic cholangiocarcinoma is an aggressive primary liver cancer
originating in the intrahepatic bile ducts. While surgical resection is the only curative …

Aging involves progressive physiological and metabolic reprogramming to adapt to gradual
deterioration of organs and functions. This includes mechanisms of defense against pre …

Objective To summarize the efficacy and safety of thermal ablation for the treatment of
intrahepatic cholangiocarcinoma (ICC). Methods MEDLINE, EMBASE, Cochran Library, and …

Intrahepatic cholangiocarcinoma (ICC) is a rare, aggressive cancer of the biliary tract. It often
presents with locally advanced or metastatic disease, but for patients with early-stage …