Minimally invasive approaches for the early detection of endometrial cancer

Y Shen, W Yang, J Liu, Y Zhang - Molecular cancer, 2023 - Springer
Endometrial cancer (EC) is one of the most common gynecologic cancers and its incidence
is rising globally. Although advanced EC has a poor prognosis; diagnosing EC at an earlier …

Current and emerging prognostic biomarkers in endometrial cancer

K Njoku, CE Barr, EJ Crosbie - Frontiers in Oncology, 2022 - frontiersin.org
Endometrial cancer is the most common gynaecological malignancy in high income
countries and its incidence is rising. Whilst most women with endometrial cancer are …

The role of CTNNB1 in endometrial cancer

Ž Ledinek, M Sobočan, J Knez - Disease Markers, 2022 - Wiley Online Library
Endometrial cancer (EC) is the most common gynaecologic malignancy in the developed
countries. Recent evidence suggests that histopathological subtyping together with …

Clinical significance of clonal hematopoiesis in the interpretation of blood liquid biopsy

HT Chan, S Nagayama, YM Chin, M Otaki… - Molecular …, 2020 - Wiley Online Library
As the use of next‐generation sequencing (NGS) for plasma cell‐free DNA (cfDNA)
continues to expand in clinical settings, accurate identification of circulating tumor DNA …

Upgrading Treatment and Molecular Diagnosis in Endometrial Cancer—Driving New Tools for Endometrial Preservation?

M Dellino, M Cerbone, AS Laganà, A Vitagliano… - International Journal of …, 2023 - mdpi.com
One emerging problem for onco-gynecologists is the incidence of premenopausal patients
under 40 years of age diagnosed with stage I Endometrial Cancer (EC) who want to …

High-sensitivity mutation analysis of cell-free DNA for disease monitoring in endometrial cancer

CW Ashley, P Selenica, J Patel, M Wu, J Nincevic… - Clinical Cancer …, 2023 - AACR
Purpose: We sought to determine whether sequencing analysis of circulating cell-free DNA
(cfDNA) in patients with prospectively accrued endometrial cancer captures the mutational …

Circulating cell-free DNA or circulating tumor DNA in the management of ovarian and endometrial cancer

Q Chen, ZH Zhang, S Wang, JH Lang - OncoTargets and therapy, 2019 - Taylor & Francis
Ovarian cancer (OC) is the most lethal cancer of all gynecological malignancies, while
endometrial cancer (EC) is the most common one. Current strategies for OC/EC diagnosis …

Non-invasive detection of endometrial cancer by DNA methylation analysis in urine

R van den Helder, BMM Wever, NE van Trommel… - Clinical …, 2020 - Springer
Background The incidence of endometrial cancer is rising, and current diagnostics often
require invasive biopsy procedures. Urine may offer an alternative sample type, which is …

A review of the clinical characteristics and novel molecular subtypes of endometrioid ovarian cancer

S Chen, Y Li, L Qian, S Deng, L Liu, W Xiao… - Frontiers in …, 2021 - frontiersin.org
Ovarian cancer is one of the most common gynecologic cancers that has the highest
mortality rate. Endometrioid ovarian cancer, a distinct subtype of epithelial ovarian cancer, is …

Noninvasive detection of microsatellite instability in patients with endometrial cancer

C Casas‐Arozamena, CP Moiola, A Vilar… - … Journal of Cancer, 2023 - Wiley Online Library
The analysis of mismatch repair proteins in solid tissue is the standard of care (SoC) for the
microsatellite instability (MSI) characterization in endometrial cancer (EC). Uterine aspirates …