What have organoids and assembloids taught us about the pathophysiology of neuropsychiatric disorders?
Neuropsychiatric research has been impeded by limited access to human brain tissue,
especially from early stages of neurodevelopment when the pathophysiology of many …
especially from early stages of neurodevelopment when the pathophysiology of many …
[HTML][HTML] Beyond consciousness: Ethical, legal, and social issues in human brain organoid research and application
This study aims to provide a comprehensive review of the ethical, legal and social issues in
human brain organoid research, with a view to different types of research and applications …
human brain organoid research, with a view to different types of research and applications …
Collaborative ethics: innovating collaboration between ethicists and life scientists
JE Lunshof, J Rijssenbeek - Nature Methods, 2024 - nature.com
Scientific breakthroughs can change how we understand and live in the world, disrupting
long-held assumptions and concepts and raising new questions for philosophy and science …
long-held assumptions and concepts and raising new questions for philosophy and science …
Modeling brain disorders using transplanted organoids: beyond the short circuit
S Velasco - Cell Stem Cell, 2022 - cell.com
Human cortical organoids transplanted into the somatosensory cortex of rats integrate into
the host neural circuits, receive inputs from host cells, and can produce behavioral …
the host neural circuits, receive inputs from host cells, and can produce behavioral …
Stem cell ethics and policy: What's old is new again
I Hyun - Med, 2022 - cell.com
Stem cells are increasingly being used to model human development and disease in the
form of self-organizing embryo models, brain organoids, and neurological chimeras. These …
form of self-organizing embryo models, brain organoids, and neurological chimeras. These …
Human brain organoids and their ethical issues: Navigating the moral and social challenges between hype and underestimation
A Lavazza, AA Chinaia - EMBO reports, 2024 - embopress.org
Since the field of neuroethics was estab-lished in the early 2000s, some scholars have
proposed to distinguish between anticipatory and speculative neuroethics (Wexler, 2019) …
proposed to distinguish between anticipatory and speculative neuroethics (Wexler, 2019) …
Pioneering neurohackers: between egocentric human enhancement and altruistic sacrifice
G Seyfried, S Youssef, M Schmidt - Frontiers in Neuroscience, 2023 - frontiersin.org
The growing field of neurotechnology (NT) is becoming more and more accessible in terms
of reduced costs, increasing availability and reliability of materials, and ways to implant …
of reduced costs, increasing availability and reliability of materials, and ways to implant …
From an ethics 'side dish'to 'your modus operandi': neurotechnology researcher perspectives on the impacts of a decade of embedded ethics collaboration
PA Tubig, TE Brown, D McCusker, M Pham… - Journal of …, 2024 - Taylor & Francis
In this paper, we discuss ethics integration and consider questions about evaluating the
success of such efforts by reporting qualitative data from an interview study with researchers …
success of such efforts by reporting qualitative data from an interview study with researchers …
The End of Personification: The Mereological Fallacy in Science Communication on Brain Organoids
SAL van Till, EM Bunnik - The American Journal of Bioethics, 2024 - Taylor & Francis
In the last two decades, stem cell-based brain organoids have been developed to study
disease mechanisms in various neurological, psychiatric, and developmental disorders …
disease mechanisms in various neurological, psychiatric, and developmental disorders …
Too-Many-Oids: the paradox in constructing an organoid ethics framework
AJ Barnhart, K Dierickx - Molecular Psychology: Brain …, 2023 - molecularpsychology.org
Background: The field of organoid ethics is complex and multifaceted, and the need for
flexibility and adaptability in the face of its moral complexity is of great importance. Certain …
flexibility and adaptability in the face of its moral complexity is of great importance. Certain …