Women are particularly more vulnerable to tobacco use than men. This review proposes a
unifying hypothesis that females experience greater rewarding effects of nicotine and more …

Obesity has reached pandemic proportions and is associated with severe comorbidities,
such as type 2 diabetes mellitus, hepatic and cardiovascular diseases, and certain cancer …

INTRODUCTION: Stereotaxic administration of neuroactive agents, either in ventricles, or
targeted at specific intracranial sites, is a widely employed strategy for neurological studies …

The opioid-mesolimbic-dopamine circuitry operates between ventral tegmental area (VTA)
and nucleus accumbens (Acb) and serves as a major reward pathway. We hypothesized …

Objective: Although hyperphagia and body weight gain are well-recognized consequences
of social isolation, the underlying mechanisms are not understood. The aim of this work is to …

BACKGROUND AND PURPOSE Agmatine, a multifaceted neurotransmitter, is abundantly
expressed in the hypothalamic paraventricular nucleus (PVN). Our aim was to assess (i) the …

While nicotine treatment to rodents causes a transient anorexia and persistent weight loss,
withdrawal produces hyperphagia and weight gain. Herein, we test the hypothesis that …

AIMS: Neuropeptide Y (NPY) is widely distributed throughout the brain and has been
implicated in some of the actions of ethanol. The aim of the present study was to …

Cocaine-and amphetamine-regulated transcript peptide (CART) is a major anorectic agent
present in the hypothalamus. We investigated the possible role of CART in mammary cancer …

Depression is a major comorbidity factor of diabetes and the outcome of one disorder
influences the other. Our aim is to scrutinize the link between the two, if any. Since …