Chemoselective CH functionalisation of aliphatic azacycles: utilisation of electrophilic iodine as a mild oxidant
RJ Griffiths - 2018 - stax.strath.ac.uk
Over half of the small molecules approved for use in the USA by the FDA in 2012 contained
at least one nitrogen heterocycle. Of these, 11% contained a piperidine motif, emphasising …
at least one nitrogen heterocycle. Of these, 11% contained a piperidine motif, emphasising …
Study and Development of Boron-mediated Amidation Reactions
V Karaluka - 2017 - discovery.ucl.ac.uk
This thesis discusses the study and further developments of boron-mediated amidation
reactions. Chapter I introduces the conventional and recent methods and developments for …
reactions. Chapter I introduces the conventional and recent methods and developments for …
Novel approaches to medium rings, enantiomerically enriched alcohols and haloalkynes
F Rota - 2012 - discovery.ucl.ac.uk
Medium rings (8-12 atoms) are present in many naturally occurring molecules which in
many cases have potentially useful biological activity. Unfortunately current synthetic …
many cases have potentially useful biological activity. Unfortunately current synthetic …