[HTML][HTML] Microfluidic platforms for cell cultures and investigations

ML Coluccio, G Perozziello, N Malara, E Parrotta… - Microelectronic …, 2019 - Elsevier
This review covers several aspects of microfluidic devices used for culturing and monitoring
of both adherent and non-adherent cells, including a multitude of applications. A comparison …

Microfluidic blood cell sorting: now and beyond

ZTF Yu, KM Aw Yong, J Fu - Small, 2014 - Wiley Online Library
Blood plays an important role in homeostatic regulation with each of its cellular components
having important therapeutic and diagnostic uses. Therefore, separation and sorting of …

Recent advances in microfluidic technology for manipulation and analysis of biological cells (2007–2017)

MK Alam, E Koomson, H Zou, C Yi, CW Li, T Xu… - Analytica chimica …, 2018 - Elsevier
The pivotal role of microfluidic technology in life science and biomedical research is now
widely recognized. Indeed, microfluidics as a research tool is unparalleled in terms of its …

Ex-vivo characterization of circulating colon cancer cells distinguished in stem and differentiated subset provides useful biomarker for personalized metastatic risk …

N Malara, V Trunzo, U Foresta, N Amodio… - Journal of Translational …, 2016 - Springer
Abstract Background Circulating tumor cells (CTCs) represent one of the most interesting
target in improving diagnosis, prognosis and treatment. Herein we evaluate the possibility of …

UbcH10 a major actor in cancerogenesis and a potential tool for diagnosis and therapy

I Presta, F Novellino, A Donato, D La Torre… - International Journal of …, 2020 - mdpi.com
Malignant transformation is a multistep process in which several molecular entities become
dysregulated and result in dysfunction in the regulation of cell proliferation. In past years …

Microfluidic systems for neural cell studies

E Babaliari, A Ranella, E Stratakis - Bioengineering, 2023 - mdpi.com
Whereas the axons of the peripheral nervous system (PNS) spontaneously regenerate after
an injury, the occurring regeneration is rarely successful because axons are usually directed …

Creating a capture zone in microfluidic flow greatly enhances the throughput and efficiency of cancer detection

M Sun, J Xu, JG Shamul, X Lu, S Husain, X He - Biomaterials, 2019 - Elsevier
Efficient capture of rare circulating tumor cells (CTCs) from blood samples is valuable for
early cancer detection to improve the management of cancer. In this work, we developed a …

A passive microfluidic device for chemotaxis studies

ML Coluccio, MA D'Attimo, CM Cristiani, P Candeloro… - Micromachines, 2019 - mdpi.com
This work presents a disposable passive microfluidic system, allowing chemotaxis studies,
through the generation of a concentration gradient. The device can handle liquid flows …

Galectin-3 coats the membrane of breast cells and makes a signature of tumours

G Simone, N Malara, V Trunzo, M Renne… - Molecular …, 2014 - pubs.rsc.org
Galectin-3, β-galactoside-binding lectin, coats the membrane of most cancer cells and is
involved in metastasis and endothelium recognition as well as in evading immune …

[HTML][HTML] A disposable passive microfluidic device for cell culturing

F Guzzi, P Candeloro, ML Coluccio, CM Cristiani… - Biosensors, 2020 - mdpi.com
In this work, a disposable passive microfluidic device for cell culturing that does not require
any additional/external pressure sources is introduced. By regulating the height of fluidic …