[HTML][HTML] Formation of templated inclusions in a forebrain α-synuclein mouse model is independent of LRRK2
DJ Dues, Y Ma, APT Nguyen, AV Offerman… - Neurobiology of …, 2023 - Elsevier
Leucine-rich repeat kinase 2 (LRRK2) and α-synuclein share enigmatic roles in the
pathobiology of Parkinson's disease (PD). LRRK2 mutations are a common genetic cause of …
pathobiology of Parkinson's disease (PD). LRRK2 mutations are a common genetic cause of …
Amygdala-predominant α-synuclein pathology exacerbates hippocampal neuron loss in Alzheimer's disease
Misfolded α-synuclein (αSyn) protein accumulates in 43-63% of individuals with
symptomatic Alzheimer's disease (AD). Two main patterns of co-morbid αSyn pathology …
symptomatic Alzheimer's disease (AD). Two main patterns of co-morbid αSyn pathology …
Adult-Onset Deletion of ATP13A2 in Mice Induces Progressive Nigrostriatal Pathway Dopaminergic Degeneration and Lysosomal Abnormalities
ML Erb, K Sipple, N Levine, X Chen, DJ Moore - bioRxiv, 2024 - biorxiv.org
Although most cases of Parkinson's disease (PD) are sporadic, mutations in over 20 genes
are known to cause heritable forms of PD. A surprising number of familial PD-linked genes …
are known to cause heritable forms of PD. A surprising number of familial PD-linked genes …