Pharmacology and therapeutic implications of current drugs for type 2 diabetes mellitus

AA Tahrani, AH Barnett, CJ Bailey - Nature Reviews Endocrinology, 2016 - nature.com
Type 2 diabetes mellitus (T2DM) is a global epidemic that poses a major challenge to health-
care systems. Improving metabolic control to approach normal glycaemia (where practical) …

Management of type 2 diabetes: new and future developments in treatment

AA Tahrani, CJ Bailey, S Del Prato, AH Barnett - The Lancet, 2011 - thelancet.com
The increasing prevalence, variable pathogenesis, progressive natural history, and
complications of type 2 diabetes emphasise the urgent need for new treatment strategies …

Green synthesis of zinc oxide nanoparticles using Hibiscus subdariffa leaf extract: effect of temperature on synthesis, anti-bacterial activity and anti-diabetic activity

N Bala, S Saha, M Chakraborty, M Maiti, S Das… - RSC Advances, 2015 - pubs.rsc.org
Zinc oxide (ZnO) nanoparticles (NPs) have been synthesized using Hibiscus subdariffa leaf
extract. Temperature dependent synthesis and particle growth have been studied. Formation …

[HTML][HTML] Anti-diabetic effect of cotreatment with quercetin and resveratrol in streptozotocin-induced diabetic rats

DK Yang, HS Kang - Biomolecules & therapeutics, 2018 - ncbi.nlm.nih.gov
Quercetin and resveratrol are known to have beneficial effects on the diabetes and diabetic
complication, however, the effects of combined treatment of these compounds on diabetes …

[HTML][HTML] Antidiabetic activity of zinc oxide and silver nanoparticles on streptozotocin-induced diabetic rats

A Alkaladi, AM Abdelazim, M Afifi - International journal of molecular …, 2014 - mdpi.com
The use of nanoparticles in medicine is an attractive proposition. In the present study, zinc
oxide and silver nanoparticles were evaluated for their antidiabetic activity. Fifty male albino …

Saponins: Anti-diabetic principles from medicinal plants–A review

OO Elekofehinti - Pathophysiology, 2015 - Elsevier
Diabetes mellitus (DM) represents a global health problem. It is the most common of the
endocrine disorders and is characterized by chronic hyperglycemia due to relative or …

A comprehensive study on antidiabetic and antibacterial activities of ZnO nanoparticles biosynthesized using Silybum marianum L seed extract

FM Arvanag, A Bayrami, A Habibi-Yangjeh… - Materials Science and …, 2019 - Elsevier
Green synthesis of ZnO nanoparticles (NPs) using the plants' extract and their potential
application have driven a tremendous interest in recent years. This study reports a green …

Pharmacology of dipeptidyl peptidase-4 inhibitors: similarities and differences

R Baetta, A Corsini - Drugs, 2011 - Springer
Abstract The dipeptidyl peptidase (DPP)-4 inhibitors, which enhance glucose-dependent
insulin secretion from pancreatic β cells by preventing DPP-4-mediated degradation of …

Characterization and hypoglycemic effect of a polysaccharide extracted from the fruit of Lycium barbarum L.

J Zhu, W Liu, J Yu, S Zou, J Wang, W Yao, X Gao - Carbohydrate polymers, 2013 - Elsevier
Diabetes mellitus is a group of complicated metabolic disorders characterized by high blood
glucose level and inappropriate insulin secreting capacity due to decreased glucose …

Implementing a low-carbohydrate, ketogenic diet to manage type 2 diabetes mellitus

EC Westman, J Tondt, E Maguire… - Expert review of …, 2018 - Taylor & Francis
Introduction: Type 2 diabetes mellitus (T2DM) has reached epidemic proportions in the
modern world. For individuals affected by obesity-related T2DM, clinical studies have shown …