Fast activation maximization for molecular sequence design

J Linder, G Seelig - BMC bioinformatics, 2021 - Springer
Background Optimization of DNA and protein sequences based on Machine Learning
models is becoming a powerful tool for molecular design. Activation maximization offers a …

Fast differentiable DNA and protein sequence optimization for molecular design

J Linder, G Seelig - arXiv preprint arXiv:2005.11275, 2020 - arxiv.org
Designing DNA and protein sequences with improved function has the potential to greatly
accelerate synthetic biology. Machine learning models that accurately predict biological …

DNA strand generation for DNA computing by using a multi-objective differential evolution algorithm

JM Chaves-Gonzalez, MA Vega-Rodriguez - Biosystems, 2014 - Elsevier
In this paper, we use an adapted multi-objective version of the differential evolution (DE)
metaheuristics for the design and generation of reliable DNA libraries that can be used for …

A multiobjective swarm intelligence approach based on artificial bee colony for reliable DNA sequence design

JM Chaves-González, MA Vega-Rodríguez… - … Applications of Artificial …, 2013 - Elsevier
The design of reliable DNA sequences is crucial in many engineering applications which
depend on DNA-based technologies, such as nanotechnology or DNA computing. In these …

A multiobjective approach based on the behavior of fireflies to generate reliable DNA sequences for molecular computing

JM Chaves-González, MA Vega-Rodríguez - Applied Mathematics and …, 2014 - Elsevier
The reliability of artificially generated DNA molecules is a key factor for applications which
depend on DNA-based technologies, such as DNA computing or nanotechnology. In those …

An efficient design for a multi-objective evolutionary algorithm to generate DNA libraries suitable for computation

JM Chaves-González, J Martínez-Gil - … Sciences: Computational Life …, 2019 - Springer
The design of reliable DNA libraries that can be used for bio-molecular computing involves
several heterogeneous conflicting design criteria that traditional optimization approaches do …

A Study on the Parameter Selection of Bat Algorithm in in Optimizing Parameters in Camera Auto Calibration Problem

RM Said, KAA Aziz, AFZ Abidin… - … Journal of Intelligent …, 2022 - journal.ump.edu.my
In camera auto calibration, the major goal is to discover intrinsic parameter values that
minimize the cost function. This study proposes to implement Bat algorithm, a stochastic …

Job scheduling using ant colony optimization in grid environment

A Chhabra - 2016 International Conference on Electrical …, 2016 - ieeexplore.ieee.org
Grid computing proposes a dynamic and earthly distributed organization of resources that
harvest ideal CPU cycle to drift advance computing demands and accommodate user's …

Hybrid multiobjective metaheuristics for the design of reliable DNA libraries

JM Chaves-González - Journal of Heuristics, 2015 - Springer
DNA-based technologies, such as nanotechnology, DNA sequencing or DNA computing,
have grown significantly in recent years. The inherent properties presented in DNA …

DNA sequence design for reliable DNA computing by using a multiobjective approach

JM Chaves-González… - 2012 IEEE 13th …, 2012 - ieeexplore.ieee.org
In DNA computing, the design of reliable DNA sequences is one of the most important tasks,
because sequences used for that purpose have to fulfill several biochemical restrictions to …