Updated international consensus report on the investigation and management of primary immune thrombocytopenia
Over the last decade, there have been numerous developments and changes in treatment
practices for the management of patients with immune thrombocytopenia (ITP). This article is …
practices for the management of patients with immune thrombocytopenia (ITP). This article is …
Splenectomy for immune thrombocytopenia: down but not out
S Chaturvedi, DM Arnold… - Blood, The Journal of the …, 2018 - ashpublications.org
Splenectomy is an effective therapy for steroid-refractory or dependent immune
thrombocytopenia (ITP). With the advent of medical alternatives such as rituximab and …
thrombocytopenia (ITP). With the advent of medical alternatives such as rituximab and …
Desialylation is a mechanism of Fc-independent platelet clearance and a therapeutic target in immune thrombocytopenia
Immune thrombocytopenia (ITP) is a common bleeding disorder caused primarily by
autoantibodies against platelet GPIIbIIIa and/or the GPIb complex. Current theory suggests …
autoantibodies against platelet GPIIbIIIa and/or the GPIb complex. Current theory suggests …
Immune thrombocytopenia-current diagnostics and therapy: recommendations of a joint working group of DGHO, ÖGHO, SGH, GPOH, and DGTI
A Matzdorff, O Meyer, H Ostermann, V Kiefel… - Oncology research and …, 2018 - karger.com
Immune thrombocytopenia (ITP) is a rare disorder and meets the criteria for an orphan
disease. Expertise in the management of these patients is not widely spread. The following …
disease. Expertise in the management of these patients is not widely spread. The following …
How I treat immune thrombocytopenia: the choice between splenectomy or a medical therapy as a second-line treatment
The paradigm for managing primary immune thrombocytopenia (ITP) in adults has changed
with the advent of rituximab and thrombopoietin receptor agonists (TPO-RAs) as options for …
with the advent of rituximab and thrombopoietin receptor agonists (TPO-RAs) as options for …
Pathophysiology of immune thrombocytopenia
Recent evidence of distinct ITP pathophysiology has opened new exploratory avenues for
disease management. We will discuss the utility of investigations into these mechanisms of …
disease management. We will discuss the utility of investigations into these mechanisms of …
State of the art–how I manage immune thrombocytopenia
N Cooper - British journal of haematology, 2017 - Wiley Online Library
The management of patients with immune thrombocytopenia (ITP) is rapidly evolving. Over
the last 15 years, a number of novel treatments have improved practice, with many steroid …
the last 15 years, a number of novel treatments have improved practice, with many steroid …
Current management of primary immune thrombocytopenia
D Provan, AC Newland - Advances in therapy, 2015 - Springer
Primary immune thrombocytopenia is an autoimmune disorder of unknown cause affecting
both children and adults. The low peripheral blood platelet count is caused by premature …
both children and adults. The low peripheral blood platelet count is caused by premature …
[HTML][HTML] Splenectomy as a curative treatment for immune thrombocytopenia: a retrospective analysis of 233 patients with a minimum follow up of 10 years
N Vianelli, F Palandri, N Polverelli, R Stasi… - …, 2013 - ncbi.nlm.nih.gov
The treatment of choice in steroid-resistant immune thrombocytopenia is still controversial
due to the recent advent of new drugs (anti-CD20 antibodies and thrombopoietin mimetics) …
due to the recent advent of new drugs (anti-CD20 antibodies and thrombopoietin mimetics) …
A critical appraisal of the evidence for the role of splenectomy in adults and children with ITP
F Rodeghiero - British journal of haematology, 2018 - Wiley Online Library
In primary chronic immune thrombocytopenia, long‐term response to splenectomy, with 60%
of patients enjoying a treatment‐free life, is higher when compared with rituximab and …
of patients enjoying a treatment‐free life, is higher when compared with rituximab and …