Excitotoxicity is a phenomenon that describes the toxic actions of excitatory
neurotransmitters, primarily glutamate, where the exacerbated or prolonged activation of …

With the acceleration of population aging, nervous system diseases including Alzheimer's
disease (AD), Parkinson's disease (PD), Huntington's disease (HD), anxiety, depression …

Neuroinflammation is one of the host defensive mechanisms through which the nervous
system protects itself from pathogenic and or infectious insults. Moreover, neuroinflammation …

Mitochondria are major sources of reactive oxygen species (ROS) within the cell and are
especially vulnerable to oxidative stress. Oxidative damage to mitochondria results in …

The high-fat, low-carbohydrate ketogenic diet (KD) is an established treatment for drug-
resistant epilepsy with a proven efficacy. The KD is being explored for Febrile Infection …

Redox biology is at the core of life sciences, accompanied by the close correlation of redox
processes with biological activities. Redox homeostasis is a prerequisite for human health …

Neuroinflammation and reactive oxygen and nitrogen species are rapidly induced in the
brain after acute cerebral injuries that are associated with an enhanced risk for epilepsy in …

Rationally designed multi-target drugs (also termed multimodal drugs, network therapeutics,
or designed multiple ligands) have emerged as an attractive drug discovery paradigm in the …

Introduction Epilepsy is a chronic neurological condition characterized by behavioral,
molecular, and neurochemical alterations. Current antiepileptic drugs are associated with …

The roles of both neuroinflammation and oxidative stress in the pathophysiology of epilepsy
have begun to receive considerable attention in recent years. However, these concepts are …