The Rho GTPases regulate many cellular signaling cascades that modulate cell motility,
migration, morphology and cell division. A large body of work has now delineated the …

Regenerative medicine is continuously facing new challenges and it is searching for new
biocompatible, green/natural polymer materials, possibly biodegradable and non …

Processing of hydrogels represents a main challenge for the prospective application of
additive manufacturing (AM) to soft tissue engineering. Furthermore, direct manufacturing of …

Stem cell therapy is promising for treating traumatic injuries of the central nervous system,
where a major challenge is to effectively differentiate neural stem cells into neurons with …

Osteocyte network architecture is closely associated with bone turnover. The cellular
mechanosensing system regulates osteocyte dendrite formation by enhancing focal …

Topographical cues on materials can manipulate cellular fate, particularly for neural cells
that respond well to such cues. Utilizing biomaterial surfaces with topographical features can …

Nerve regeneration and recovery could provide great therapeutic benefits for individuals
suffering from nerve damage post trauma or degenerative diseases. However, manipulation …

Smart electroactive biomaterials are sought to allow the direct delivery of electrical,
electrochemical and electromechanical signals to biological tissues. Specifically, poly-(3, 4 …

In order to properly manipulate liquids into microfluidic networks, an accurate sealing of the
device is of paramount importance. Polydimethylsiloxane (PDMS) is ubiquitously used for …

Hydrogel scaffolds are particularly interesting for applications in tissue engineering because
of their ability to create a favorable environment which mimics in vivo conditions. However …