A stress paradox: the dual role of the unfolded protein response in the placenta

D Chowdhury, CE Jang, P Lajoie… - Frontiers in …, 2024 - frontiersin.org
The placenta is a temporary organ that forms during pregnancy and is essential for fetal
development and maternal health. As an endocrine organ, proper placental function …

Single-nucleus transcriptomic analysis reveals the regulatory circuitry of myofiber XBP1 during regenerative myogenesis

AS Joshi, MB Castillo, MT da Silva, AT Vuong… - iScience, 2024 - cell.com
Endoplasmic reticulum (ER) stress-induced unfolded protein response (UPR) is activated in
skeletal muscle under multiple conditions. However, the role of the UPR in the regulation of …