Background and aims The aim of this systematic review is to describe the epidemiology of
chordoma and to provide a clear overview of clinical prognostic factors predicting …

Chordoma is a complex disease because of its rarity, biological heterogeneity and peculiar
clinical behaviour. Despite the progress done, the outcome in this disease remains …

BACKGROUND The current study was conducted to evaluate the long‐term results of
irradiation with carbon ions in a raster scanning technique in patients with skull base …

Purpose To evaluate the long term tumor control and toxicity of skull base tumors treated
with pencil beam scanning proton therapy (PT). Materials and methods PT was delivered to …

Purpose: We sought to determine the mechanism of an exceptional response in a patient
diagnosed with a SMARCB1/INI1-negative chordoma treated with tazemetostat, an EZH2 …

Purpose Sacral chordomas (SC) are rare, locally invasive, malignant neoplasms. Despite
surgical resection and adjuvant therapies, local recurrence (LR) is common and overall …

Background The aim of this study is to evaluate results in terms of local control (LC), overall
survival (OS), and toxicity profile and to better identify factors influencing clinical outcome of …

Simple Summary It is unclear what the risk of negative health outcomes is after cancer
during adolescence and young adulthood. We conducted a review to understand the risk of …

Background Chordomas are rare malignant bone cancers of the skull-base and spine.
Patient survival is variable and not reliably predicted using clinical factors or molecular …

Simple Summary Surgery is the primary treatment for chordoma. However, residual or
recurrent chordoma presents a significant problem for clinicians. The aim of this work is to …