DNA methylation as a diagnostic, prognostic, and predictive biomarker in head and neck cancer

G Liouta, M Adamaki, A Tsintarakis… - International Journal of …, 2023 - mdpi.com
Head and neck squamous cell carcinoma (HNSCC) is a term collectively used to describe
all cancers that develop in the oral and nasal cavities, the paranasal sinuses, the salivary …

[HTML][HTML] Liquid biopsies based on cell-free DNA as a potential biomarker in head and neck cancer

Ó Rapado-González, AM Rodríguez-Ces… - … Dental Science Review, 2023 - Elsevier
In the era of 'precision medicine', liquid biopsies based on cell-free DNA (cfDNA) have
emerged as a promising tool in the oncology field. cfDNA from cancer patients is a mixture of …

Transcriptomic-based identification of the immuno-oncogenic signature of cholangiocarcinoma for HLC-018 multi-target therapy exploration

B Lawal, YC Kuo, SL Tang, FC Liu, ATH Wu, HY Lin… - Cells, 2021 - mdpi.com
Cholangiocarcinomas (CHOLs), hepatobiliary malignancies, are characterized by high
genetic heterogeneity, a rich tumor microenvironment, therapeutic resistance, difficulty …

Multi-omics integration analysis of GPCRs in pan-cancer to uncover inter-omics relationships and potential driver genes

S Li, X Chen, J Chen, B Wu, J Liu, Y Guo, M Li… - Computers in Biology …, 2023 - Elsevier
G protein-coupled receptors (GPCRs) are the largest drug target family. Unfortunately,
applications of GPCRs in cancer therapy are scarce due to very limited knowledge …

Head and neck squamous cell carcinoma: epigenetic landscape

K Romanowska, A Sobecka, AA Rawłuszko-Wieczorek… - Diagnostics, 2020 - mdpi.com
Head and neck squamous carcinoma (HNSCC) constitutes the sixth most prevalent cancer
worldwide. The molecular pathogenesis of HNSCC includes disorders in cell cycle …

The MAL protein, an integral component of specialized membranes, in normal cells and cancer

A Rubio-Ramos, L Labat-de-Hoz, I Correas, MA Alonso - Cells, 2021 - mdpi.com
The MAL gene encodes a 17-kDa protein containing four putative transmembrane segments
whose expression is restricted to human T cells, polarized epithelial cells and myelin …

A systematic review on the molecular and clinical association between Human Papillomavirus and Human Immunodeficiency Virus co‐infection in Head, Neck and …

S Chakraborty, K Ramasubbu… - Reviews in Medical …, 2023 - Wiley Online Library
Head and neck cancer, one of the most commonly prevalent malignancies globally is a
complex category of tumours that comprises cancers of the oral cavity, pharynx, and larynx …

DNA methylation and HPV-associated head and neck cancer

T Nakagawa, T Kurokawa, M Mima, S Imamoto… - Microorganisms, 2021 - mdpi.com
Head and neck squamous cell carcinoma (HNSCC), especially oropharyngeal squamous
cell carcinoma (OPSCC), has recently been found to be significantly associated with human …

Fluid biomarkers in HPV and non-HPV related oropharyngeal carcinomas: from diagnosis and monitoring to prognostication—a systematic Review

SC Lee, KKC Leung, ACY Chung, ESY Wong… - International Journal of …, 2022 - mdpi.com
Biomarkers are crucial in oncology, from detection and monitoring to guiding management
and predicting treatment outcomes. Histological assessment of tissue biopsies is currently …

Identification of calmodulin‐like protein 5 as tumor‐suppressor gene silenced during early stage of carcinogenesis in squamous cell carcinoma of uterine cervix

S Kitazawa, Y Takaoka, Y Ueda… - International journal of …, 2021 - Wiley Online Library
In the course of identifying the molecular mechanism that is related to strong cell‐cell
adhesion in stratified structures of the squamous epithelium, calmodulin‐like protein 5 …