DNA-binding of nickel (II), copper (II) and zinc (II) complexes: Structure–affinity relationships

G Barone, A Terenzi, A Lauria, AM Almerico… - Coordination Chemistry …, 2013 - Elsevier
Abstract Nickel (II), copper (II) and zinc (II) complexes with the same ligands normally display
analogous coordination geometry and binding mode toward DNA. However, although …

Traversing the coordination chemistry and chemical biology of hydroxamic acids

R Codd - Coordination Chemistry Reviews, 2008 - Elsevier
Hydroxamic acids, RCC (O) N (RN) OH (RC= alkyl/aryl; RN= alkyl/aryl or H), coordinate a
wide variety of transition metal ions predominantly as the monoanionic hydroxamato or …

Hydroxamic acid: an underrated moiety? Marrying bioinorganic chemistry and polymer science

J Keth, T Johann, H Frey - Biomacromolecules, 2020 - ACS Publications
Even 150 years after their discovery, hydroxamic acids are mainly known as the starting
material for the Lossen rearrangement in textbooks. However, hydroxamic acids feature a …

Anticancer activity and DNA binding of a bifunctional Ru (II) arene aqua-complex with the 2, 4-diamino-6-(2-pyridyl)-1, 3, 5-triazine ligand

N Busto, J Valladolid, M Martinez-Alonso… - Inorganic …, 2013 - ACS Publications
The synthesis and full characterization of the new aqua-complex [(η6-p-cymene) Ru
(OH2)(κ2-N, N-2-pydaT)](BF4) 2,[2](BF 4) 2, and the nucleobase derivative [(η6-p-cymene) …

Viral enzymes containing magnesium: Metal binding as a successful strategy in drug design

D Rogolino, M Carcelli, M Sechi, N Neamati - Coordination Chemistry …, 2012 - Elsevier
Metal-activated enzymes are important targets in drug discovery in general and for antivirals
in particular. Such proteins contain one or more metal ion cofactors, prevalently located in …

Synthesis and characterization of two new hydroxamic acids derivatives and their metal complexes. An investigation on the keto/enol, E/Z and hydroxamate …

E Adiguzel, F Yilmaz, M Emirik, M Ozil - Journal of Molecular Structure, 2017 - Elsevier
phenylbenzimidazole-N-acetohydroxamic acid (HL 1), 2-phenylbenzimidazole-N-
butanohydroxamic acid (HL 2) and Ni (II), Cu (II), Zn (II) and Cd (II) metal complexes have …

Isoprenoid biosynthesis via the methylerythritol phosphate pathway: structural variations around phosphonate anchor and spacer of fosmidomycin, a potent inhibitor of …

C Zinglé, L Kuntz, D Tritsch… - The Journal of …, 2010 - ACS Publications
Fosmidomycin and its analogue FR-900098 are potent inhibitors of 1-deoxy-d-xylulose 5-
phosphate reducto-isomerase (DXR), the second enzyme of the MEP pathway for the …

Poly (hydroxamic acid) resins and their applications

ML Rahman, MS Sarjadi, SM Sarkar, DJ Walsh… - Coordination Chemistry …, 2022 - Elsevier
Functional residues of hydroxamic acid render the organic molecule amenable to the
formation of chelates with a wide range of metals especially those classed as transition …

Dynamic 1H NMR Study of the Barrier to Rotation about the C−N Bond in Primary Carbamates and Its Solvent Dependence

AR Modarresi-Alam, P Najafi… - The Journal of …, 2007 - ACS Publications
The dynamic 1H NMR study of some primary carbamates in the solvents CDCl3 and
CD3COCD3 between 183 and 298 K is reported. The free energies of activation, thus …

Conformations, protonation sites, and metal complexation of benzohydroxamic acid. A theoretical and experimental study

B García, S Ibeas, JM Leal, F Secco… - Inorganic …, 2005 - ACS Publications
A theoretical and experimental study on the structure and deprotonation of
benzohydroxamic acid (BHA) has been performed. Calculations at the RHF/cc-pVDZ level …