Emerging viruses and current strategies for vaccine intervention
During the past decade several notable viruses have suddenly emerged from obscurity or
anonymity to become serious global health threats, provoking concern regarding their …
anonymity to become serious global health threats, provoking concern regarding their …
Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
FF Gonzalez-Galarza, A McCabe… - Nucleic acids …, 2020 - academic.oup.com
Abstract The Allele Frequency Net Database (AFND, www. allelefrequencies. net) provides
the scientific community with a freely available repository for the storage of frequency data …
the scientific community with a freely available repository for the storage of frequency data …
Epitope prediction and identification-adaptive T cell responses in humans
Epitopes, in the context of T cell recognition, are short peptides typically derived by antigen
processing, and presented on the cell surface bound to MHC molecules (HLA molecules in …
processing, and presented on the cell surface bound to MHC molecules (HLA molecules in …
Designing multi-epitope vaccines to combat emerging coronavirus disease 2019 (COVID-19) by employing immuno-informatics approach
A recent pandemic caused by a single-stranded RNA virus, COVID-19, initially discovered in
China, is now spreading globally. This poses a serious threat that needs to be addressed …
China, is now spreading globally. This poses a serious threat that needs to be addressed …
Immuno-informatics profiling of monkeypox virus cell surface binding protein for designing a next generation multi-valent peptide-based vaccine
Monkeypox is a viral etiological agent with hallmarks analogous to those observed in
smallpox cases in the past. The ongoing outbreak of Monkeypox viral infection is becoming …
smallpox cases in the past. The ongoing outbreak of Monkeypox viral infection is becoming …
Recombinant and epitope-based vaccines on the road to the market and implications for vaccine design and production
Novel vaccination approaches based on rational design of B-and T-cell epitopes-epitope-
based vaccines-are making progress in the clinical trial pipeline. The epitope-focused …
based vaccines-are making progress in the clinical trial pipeline. The epitope-focused …
Current progress in developing subunit vaccines against enterotoxigenic Escherichia coli-associated diarrhea
Diarrhea continues to be a leading cause of death in children< 5 years of age, and
enterotoxigenic Escherichia coli (ETEC) is the most common bacterial cause of children's …
enterotoxigenic Escherichia coli (ETEC) is the most common bacterial cause of children's …
[HTML][HTML] Prediction of promiscuous T-cell epitopes in the Zika virus polyprotein: An in silico approach
Objective To predict immunogenic promiscuous T cell epitopes from the polyprotein of the
Zika virus using a range of bioinformatics tools. To date, no epitope data are available for the …
Zika virus using a range of bioinformatics tools. To date, no epitope data are available for the …
Major histocompatibility complex linked databases and prediction tools for designing vaccines
Presently, the major histocompatibility complex (MHC) is receiving considerable interest
owing to its remarkable role in antigen presentation and vaccine design. The specific …
owing to its remarkable role in antigen presentation and vaccine design. The specific …
The role of HLA genetic variants in COVID‐19 susceptibility, severity, and mortality: A global review
T Hoseinnezhad, N Soltani, S Ziarati… - Journal of Clinical …, 2024 - Wiley Online Library
Background The COVID‐19 pandemic has had a profound global impact, with variations in
susceptibility, severity, and mortality rates across different regions. While many factors can …
susceptibility, severity, and mortality rates across different regions. While many factors can …