Cell-free permeation systems are gaining interest in drug discovery and development as
tools to obtain a reliable prediction of passive intestinal absorption without the …

Oral buccal mucosal delivery has the advantage of avoiding gastrointestinal drug
degradation, reducing hepatic firstpass effects, and improving patient compliance. In recent …

Mucoadhesive delivery systems have attracted remarkable interest recently, especially for
their potential to prolong dosage form resident times at sites of application such as the …

Progesterone-loaded poly (lactic) acid fibrous polymeric patches were produced using
electrospinning and pressurized gyration for intra-vaginal application to prevent preterm …

The aim of the present work was to obtain drug-loaded hydrogels based on combinations of
dextran, chitosan/gelatin/xanthan, and poly (acrylamide) as a sustained and controlled …

Recent evidence has continued to support the applicability of progesterone in preventing
preterm birth, hence the development of an appropriate vaginal delivery system for this drug …

Abstract Development of buccal application forms is gaining increasing interest in recent
years, mostly driven by the insight that enabling formulations may help to overcome …

The buccal mucosa is arising within the pharmaceutical landscape as an attractive option for
local and systemic drug delivery, mostly due to its high vascularization, inherent permeability …

This study aims to develop an in vitro barrier effect test over biomimetic membrane, which is
useful to establish the film forming ability of a substance-based medical device (SB-MD) …

Progesterone, a steroidal hormone, is used as pharmacotherapy in the clinical practice of
obstetrics and gynaecology. There are however considerable bioavailability issues with the …