Use of biodegradable, chitosan-based nanoparticles in the treatment of Alzheimer's disease

E Manek, F Darvas, GA Petroianu - Molecules, 2020 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects more than
24 million people worldwide and represents an immense medical, social and economic …

Is arsenic exposure a risk factor for metabolic syndrome? a review of the potential mechanisms

P Pánico, M Velasco, AM Salazar, A Picones… - Frontiers in …, 2022 - frontiersin.org
Exposure to arsenic in drinking water is a worldwide health problem. This pollutant is
associated with increased risk of developing chronic diseases, including metabolic …

Morroniside interaction with poly (ADP-ribose) polymerase accentuates metabolic mitigation of alloxan-induced genotoxicity and hyperglycaemia: a molecular docking …

S Dey, I Nagpal, P Sow, R Dey… - Journal of …, 2023 - Taylor & Francis
The present study tends to evaluate the possible potential of bio-active Morroniside (MOR),
against alloxan (ALX)-induced genotoxicity and hyperglycaemia. In silico prediction …

Nanomedicine based on natural products: improving clinical application potential

Z Li, T Zhao, J Li, Q Yu, Y Feng, Y Xie… - Journal of …, 2022 - Wiley Online Library
Natural products have antitumor, anti‐inflammatory, antioxidant, and other pharmacological
activities and are an important source of drugs for prevention and treatment of various …

Strategic formulation of apigenin-loaded PLGA nanoparticles for intracellular trafficking, DNA targeting and improved therapeutic effects in skin melanoma in vitro

S Das, J Das, A Samadder, A Paul, AR Khuda-Bukhsh - Toxicology letters, 2013 - Elsevier
The aim of the present study was the evaluation of anti-proliferative potentials of apigenin
(Ap),(a dietary flavonoid) loaded in poly (lactic-co-glycolide) nanoparticles (NAp) in A375 …

Poly lactide-co-glycolide encapsulated nano-curcumin promoting antagonistic interactions between HSP 90 and XRCC1 proteins to prevent cypermethrin-induced …

P Sow, S Dey, R Dey, A Majumder, S Nandi… - Colloids and Surfaces B …, 2022 - Elsevier
The present study describes the preparation and characterization of poly-lactide-co-
glycolide encapsulated nano-curcumin (NCUR) drug, and its potential efficacy against the …

Pelargonidin mediated selective activation of p53 and parp proteins in preventing food additive induced genotoxicity: an in vivo coupled in silico molecular docking …

R Dey, S Nandi, A Samadder - European Journal of Pharmaceutical …, 2021 - Elsevier
Food-additive toxicity has become a major health hazard issue globally. Alloxan (ALX), a
food-additive, intaken daily through flour causes diabetes and genotoxicity by inducing …

[HTML][HTML] Current naturopathy to combat Alzheimer's disease

A Chakrovorty, B Bhattacharjee, A Saxena… - Current …, 2023 - ncbi.nlm.nih.gov
Neurodegeneration is the progressive loss of structure or function of neurons, which may
ultimately involve cell death. The most common neurodegenerative disorder in the brain …

Nanopharmaceutical approach using pelargonidin towards enhancement of efficacy for prevention of alloxan-induced DNA damage in L6 cells via activation of PARP …

A Samadder, SK Abraham… - Environmental Toxicology …, 2016 - Elsevier
Alloxan is an environmental food contaminant that causes DNA damage in living cells and
induces hyperglycemia. Pelargonidin (PG), an active ingredient found in extract of various …

Brain delivery of antidotes by polymeric nanoparticles

E Manek, GA Petroianu - Journal of Applied Toxicology, 2021 - Wiley Online Library
Accidental intoxications from environmental pollutants, as well as intentional self‐and
chemical warfare‐related poisonings affect millions of people worldwide each year. While …