The biomedical use of silk: past, present, future

C Holland, K Numata… - Advanced healthcare …, 2019 - Wiley Online Library
Humans have long appreciated silk for its lustrous appeal and remarkable physical
properties, yet as the mysteries of silk are unraveled, it becomes clear that this outstanding …

Fiber‐based biopolymer processing as a route toward sustainability

C Li, J Wu, H Shi, Z Xia, JK Sahoo, J Yeo… - Advanced …, 2022 - Wiley Online Library
Some of the most abundant biomass on earth is sequestered in fibrous biopolymers like
cellulose, chitin, and silk. These types of natural materials offer unique and striking …

Uncovering the structure–function relationship in spider silk

JL Yarger, BR Cherry, A Van Der Vaart - Nature Reviews Materials, 2018 - nature.com
All spiders produce protein-based biopolymer fibres that we call silk. The most studied of
these silks is spider dragline silk, which is very tough and relatively abundant compared with …

Progress and trends in artificial silk spinning: a systematic review

A Koeppel, C Holland - ACS Biomaterials Science & Engineering, 2017 - ACS Publications
More than 400 million years of natural selection acting throughout the arthropoda has
resulted in highly specialized and energetically efficient processes to produce protein-based …

Spider silk: from soluble protein to extraordinary fiber

M Heim, D Keerl, T Scheibel - … Chemie International Edition, 2009 - Wiley Online Library
On a silky thread: Spider silks have mechanical properties that outperform most natural and
synthetic fibers. Classical spinning methods have failed to mimic the highly complex natural …

Enzymatic Degradation of Bombyx mori Silk Materials: A Review

C Guo, C Li, DL Kaplan - Biomacromolecules, 2020 - ACS Publications
As a biomaterial, silk presents unique features with a combination of excellent mechanical
properties, biocompatibility, and biodegradability. The biodegradability aspects of silk …

Structure–function–property–design interplay in biopolymers: Spider silk

O Tokareva, M Jacobsen, M Buehler, J Wong… - Acta biomaterialia, 2014 - Elsevier
Spider silks have been a focus of research for almost two decades due to their outstanding
mechanical and biophysical properties. Recent advances in genetic engineering have led to …

Analysis of the Structure of Bombyx mori Silk Fibroin by NMR

T Asakura, K Okushita, MP Williamson - Macromolecules, 2015 - ACS Publications
The past 15 years have seen a major increase in our understanding of the structure and
dynamics of Bombyx mori silk fibroin, largely as a result of NMR studies. We now have a …

Direct‐write assembly of microperiodic silk fibroin scaffolds for tissue engineering applications

S Ghosh, ST Parker, X Wang… - Advanced Functional …, 2008 - Wiley Online Library
Three–dimensional, microperiodic scaffolds of regenerated silk fibroin have been fabricated
for tissue engineering by direct ink writing. The ink, which consisted of silk fibroin solution …

Silk self-assembly mechanisms and control from thermodynamics to kinetics

Q Lu, H Zhu, C Zhang, F Zhang, B Zhang… - …, 2012 - ACS Publications
Silkworms and spiders generate fibers that exhibit high strength and extensibility. The
underlying mechanisms involved in processing silk proteins into fiber form remain …