Gradients and consequences of heterogeneity in biofilms

J Jo, A Price-Whelan, LEP Dietrich - Nature Reviews Microbiology, 2022 - nature.com
Historically, appreciation for the roles of resource gradients in biology has fluctuated
inversely to the popularity of genetic mechanisms. Nevertheless, in microbiology specifically …

The oral microbiota: dynamic communities and host interactions

RJ Lamont, H Koo, G Hajishengallis - Nature reviews microbiology, 2018 - nature.com
The dynamic and polymicrobial oral microbiome is a direct precursor of diseases such as
dental caries and periodontitis, two of the most prevalent microbially induced disorders …

Polymicrobial communities in periodontal disease: Their quasi‐organismal nature and dialogue with the host

G Hajishengallis, RJ Lamont - Periodontology 2000, 2021 - Wiley Online Library
In health, indigenous polymicrobial communities at mucosal surfaces maintain an ecological
balance via both inter‐microbial and host‐microbial interactions that promote their own and …

A decade of advances in transposon-insertion sequencing

AK Cain, L Barquist, AL Goodman, IT Paulsen… - Nature Reviews …, 2020 - nature.com
It has been 10 years since the introduction of modern transposon-insertion sequencing (TIS)
methods, which combine genome-wide transposon mutagenesis with high-throughput …

Oral polymicrobial communities: Assembly, function, and impact on diseases

G Hajishengallis, RJ Lamont, H Koo - Cell host & microbe, 2023 - cell.com
Oral microbial communities assemble into complex spatial structures. The sophisticated
physical and chemical signaling systems underlying the community enable their collective …

Gut microbiota-produced tryptamine activates an epithelial G-protein-coupled receptor to increase colonic secretion

Y Bhattarai, BB Williams, EJ Battaglioli, WR Whitaker… - Cell host & …, 2018 - cell.com
Tryptamine, a tryptophan-derived monoamine similar to 5-hydroxytryptamine (5-HT), is
produced by gut bacteria and is abundant in human and rodent feces. However, the …

Infection trains the host for microbiota-enhanced resistance to pathogens

A Stacy, V Andrade-Oliveira, JA McCulloch, B Hild… - Cell, 2021 - cell.com
The microbiota shields the host against infections in a process known as colonization
resistance. How infections themselves shape this fundamental process remains largely …

Host microbiota can facilitate pathogen infection

EJ Stevens, KA Bates, KC King - PLoS pathogens, 2021 - journals.plos.org
Animals live in symbiosis with numerous microbe species. While some can protect hosts
from infection and benefit host health, components of the microbiota or changes to the …

Oral commensal streptococci: gatekeepers of the oral cavity

JJ Baty, SN Stoner, JA Scoffield - Journal of Bacteriology, 2022 - Am Soc Microbiol
Oral commensal streptococci are primary colonizers of the oral cavity. These streptococci
produce many adhesins, metabolites, and antimicrobials that modulate microbial succession …

The biogeography of polymicrobial infection

A Stacy, L McNally, SE Darch, SP Brown… - Nature Reviews …, 2016 - nature.com
Microbial communities are spatially organized in both the environment and the human body.
Although patterns exhibited by these communities are described by microbial biogeography …