Gradients and consequences of heterogeneity in biofilms
Historically, appreciation for the roles of resource gradients in biology has fluctuated
inversely to the popularity of genetic mechanisms. Nevertheless, in microbiology specifically …
inversely to the popularity of genetic mechanisms. Nevertheless, in microbiology specifically …
The oral microbiota: dynamic communities and host interactions
RJ Lamont, H Koo, G Hajishengallis - Nature reviews microbiology, 2018 - nature.com
The dynamic and polymicrobial oral microbiome is a direct precursor of diseases such as
dental caries and periodontitis, two of the most prevalent microbially induced disorders …
dental caries and periodontitis, two of the most prevalent microbially induced disorders …
Polymicrobial communities in periodontal disease: Their quasi‐organismal nature and dialogue with the host
G Hajishengallis, RJ Lamont - Periodontology 2000, 2021 - Wiley Online Library
In health, indigenous polymicrobial communities at mucosal surfaces maintain an ecological
balance via both inter‐microbial and host‐microbial interactions that promote their own and …
balance via both inter‐microbial and host‐microbial interactions that promote their own and …
A decade of advances in transposon-insertion sequencing
It has been 10 years since the introduction of modern transposon-insertion sequencing (TIS)
methods, which combine genome-wide transposon mutagenesis with high-throughput …
methods, which combine genome-wide transposon mutagenesis with high-throughput …
Oral polymicrobial communities: Assembly, function, and impact on diseases
G Hajishengallis, RJ Lamont, H Koo - Cell host & microbe, 2023 - cell.com
Oral microbial communities assemble into complex spatial structures. The sophisticated
physical and chemical signaling systems underlying the community enable their collective …
physical and chemical signaling systems underlying the community enable their collective …
Gut microbiota-produced tryptamine activates an epithelial G-protein-coupled receptor to increase colonic secretion
Y Bhattarai, BB Williams, EJ Battaglioli, WR Whitaker… - Cell host & …, 2018 - cell.com
Tryptamine, a tryptophan-derived monoamine similar to 5-hydroxytryptamine (5-HT), is
produced by gut bacteria and is abundant in human and rodent feces. However, the …
produced by gut bacteria and is abundant in human and rodent feces. However, the …
Infection trains the host for microbiota-enhanced resistance to pathogens
The microbiota shields the host against infections in a process known as colonization
resistance. How infections themselves shape this fundamental process remains largely …
resistance. How infections themselves shape this fundamental process remains largely …
Host microbiota can facilitate pathogen infection
Animals live in symbiosis with numerous microbe species. While some can protect hosts
from infection and benefit host health, components of the microbiota or changes to the …
from infection and benefit host health, components of the microbiota or changes to the …
Oral commensal streptococci: gatekeepers of the oral cavity
JJ Baty, SN Stoner, JA Scoffield - Journal of Bacteriology, 2022 - Am Soc Microbiol
Oral commensal streptococci are primary colonizers of the oral cavity. These streptococci
produce many adhesins, metabolites, and antimicrobials that modulate microbial succession …
produce many adhesins, metabolites, and antimicrobials that modulate microbial succession …
The biogeography of polymicrobial infection
Microbial communities are spatially organized in both the environment and the human body.
Although patterns exhibited by these communities are described by microbial biogeography …
Although patterns exhibited by these communities are described by microbial biogeography …