Salivary biomarkers in oral squamous cell carcinoma: a proteomic overview

G Riccardi, MG Bellizzi, I Fatuzzo, F Zoccali… - Proteomes, 2022 - mdpi.com
Background: Oral squamous cell carcinoma (OSCC) is one of the most frequent cancers
worldwide. Endoscopic methods may be useful in the evaluation of oral injuries even though …

Role of salivary MicroRNA and cytokines in the diagnosis and prognosis of oral squamous cell carcinoma

FJ Manzano-Moreno, VJ Costela-Ruiz… - International journal of …, 2021 - mdpi.com
Oral squamous cell carcinoma (OSCC) is the most prevalent oral malignant tumor
worldwide. An early diagnosis can have a major positive impact on its prognosis. Human …

Resveratrol nanoparticle attenuates metastasis and angiogenesis by deregulating inflammatory cytokines through inhibition of CAFs in oral cancer by CXCL-12/IL-6 …

R Pradhan, S Paul, B Das, S Sinha, SR Dash… - The Journal of …, 2023 - Elsevier
Cancer-associated fibroblasts (CAFs) are one of the highly abundant components in the
tumor microenvironment (TME). They secrete several cytokines, which amplified tumor …

F. nucleatum facilitates oral squamous cell carcinoma progression via GLUT1-driven lactate production

J Sun, Q Tang, S Yu, M Xie, W Zheng, G Chen, Y Yin… - …, 2023 - thelancet.com
Background Tumor-resident microbiota has been documented for various cancer types. Oral
squamous cell carcinoma (OSCC) is also enriched with microbiota, while the significance of …

Digesting the role of JAK-STAT and cytokine signaling in oral and gastric cancers

Y Ni, JT Low, J Silke, LA O'Reilly - Frontiers in Immunology, 2022 - frontiersin.org
When small proteins such as cytokines bind to their associated receptors on the plasma
membrane, they can activate multiple internal signaling cascades allowing information from …

Assessing the effect of smokeless tobacco consumption on oral microbiome in healthy and oral cancer patients

R Saxena, V Prasoodanan PK, SV Gupta… - Frontiers in Cellular …, 2022 - frontiersin.org
Oral cancer is a globally widespread cancer that features among the three most prevalent
cancers in India. The risk of oral cancer is elevated by factors such as tobacco consumption …

The three-dimensional in vitro cell culture models in the study of oral cancer immune microenvironment

E Dalir Abdolahinia, X Han - Cancers, 2023 - mdpi.com
Simple Summary The extensive array of applications in 3D culture models closely mimics
the precise physiological conditions of in vivo settings, enabling the investigation of …

Tumour necrosis factor alpha (TNF-α) and oral squamous cell carcinoma

G Brierly, A Celentano, O Breik, E Moslemivayeghan… - Cancers, 2023 - mdpi.com
Simple Summary TNF-α is of interest in oral squamous cell carcinoma (OSCC), with its
demonstrated presence affecting both tumour and stromal inflammatory cells to enhance …

The role of oral microbiota in cancer

Z Lan, WJ Liu, H Cui, KL Zou, H Chen… - Frontiers in …, 2023 - frontiersin.org
Cancer remains a significant global challenge, with an estimated 47% increase in cancer
patients from 2020 to 2040. Increasing research has identified microorganism as a risk factor …

Targeted blockade of interleukin-8 negates metastasis and chemoresistance via Akt/Erk-NFκB axis in oral cancer

S Joshi, R Pandey, A Kumar, V Gupta, N Arya - Cytokine, 2023 - Elsevier
Background The tumor microenvironment plays a significant role in tumor growth, metastasis
and chemoresistance via dysregulated signaling pathways. Toward this, an inflammatory …