To enable survival in adverse conditions, cancer cells undergo global metabolic
adaptations. The amino acid cysteine actively contributes to cancer metabolic remodelling …

Hydrogen sulfide (H 2 S) is an important signaling molecule in colorectal cancer (CRC). It is
produced in the colon by the catalytic synthesis of the colonocytes' enzymatic systems and …

Metabolic reprogramming is one of the hallmarks of tumors. Alterations of cellular
metabolism not only contribute to tumor development, but also mediate the resistance of …

Ovarian cancer is a silent cancer which rate survival mainly relays in early stage detection.
The discovery of reliable ovarian cancer biomarkers plays a crucial role in the disease …

Glutathione (GSH) has several roles in a cell, such as a reactive oxygen species (ROS)
scavenger, an intervenient in xenobiotics metabolism and a reservoir of cysteine. All of these …

Hypoxia, a common factor ruling the microenvironment composition, leads to tumor
progression. In this hypoxic context, cytokines and cells cooperate to favor cancer …

Weight loss and cachexia are common problems in colorectal cancer patients; thus,
parenteral and enteral nutrition support play important roles in cancer care. However, the …

Cancer cells undergo a metabolic rewiring in order to fulfill the energy and biomass
requirements. Cysteine is a pivotal organic compound that contributes for cancer metabolic …

Per-and polyfluoroalkyl substances (PFAS) are ubiquitous environmental contaminants
associated with adverse reproductive outcomes including reproductive cancers in women …

Abstract Background The ST6Gal-I glycosyltransferase, which adds α2–6-linked sialic acids
to N-glycosylated proteins is upregulated in a wide range of malignancies including ovarian …