Reactive oxygen and nitrogen species have been implicated in diverse pathophysiological
conditions, including inflammation, neurodegenerative diseases and cancer. Accumulating …

Chronic obstructive pulmonary disease (COPD) and atherosclerosis are chronic irreversible
diseases, that share a number of common causative factors including cigarette smoking …

Ageing is accompanied by increasing vulnerability to major pathologies (atherosclerosis,
Alzheimer's disease, age-related macular degeneration, cataract, and osteoporosis) which …

The main biological cause of oxysterols is the oxidation of cholesterol. They differ from
cholesterol by the presence of additional polar groups that are typically hydroxyl, keto …

Due to the fact that one of the main causes of worldwide deaths are directly related to
atherosclerosis, scientists are constantly looking for atherosclerotic factors, in an attempt to …

Non‐enzymatic and enzymatic oxidation of lipids has long been a primary issue in human
pathophysiology, with special emphasis on diet‐and nutrition‐related aspects. While there is …

The present review aims to provide a complete and comprehensive summary of current
literature relevant to oxysterols and related diseases. Oxidation of cholesterol leads to the …

Dietary habits may strongly influence intestinal homeostasis. Oxysterols, the oxidized
products of cholesterol present in cholesterol-containing foodstuffs, have been shown to …

Human hepatocellular carcinomas (HCCs), which arise on a background of chronic liver
damage and inflammation, express c-Fos, a component of the AP-1 transcription factor …

Infections with Opisthorchis viverrini, Clonorchis sinensis, and Schistosoma haematobium
are classified as group 1 biological carcinogens: definitive causes of cancer. These worms …