Role of cadherins in cancer—a review

I Kaszak, O Witkowska-Piłaszewicz… - International journal of …, 2020 - mdpi.com
Cadherins play an important role in tissue homeostasis, as they are responsible for cell-cell
adhesion during embryogenesis, tissue morphogenesis, differentiation and carcinogenesis …

Tensile forces and mechanotransduction at cell–cell junctions

G Charras - Current Biology, 2018 - cell.com
Cell–cell junctions are specializations of the plasma membrane responsible for physically
integrating cells into tissues. We are now beginning to appreciate the diverse impacts that …

VE-cadherin in arachnoid and pia mater cells serves as a suitable landmark for in vivo imaging of CNS immune surveillance and inflammation

JA Mapunda, J Pareja, M Vladymyrov, E Bouillet… - Nature …, 2023 - nature.com
Meninges cover the surface of the brain and spinal cord and contribute to protection and
immune surveillance of the central nervous system (CNS). How the meningeal layers …

Protein interactions at endothelial junctions and signaling mechanisms regulating endothelial permeability

YA Komarova, K Kruse, D Mehta, AB Malik - Circulation research, 2017 - Am Heart Assoc
The monolayer of endothelial cells lining the vessel wall forms a semipermeable barrier (in
all tissue except the relatively impermeable blood–brain and inner retinal barriers) that …

The minimal cadherin-catenin complex binds to actin filaments under force

CD Buckley, J Tan, KL Anderson, D Hanein… - Science, 2014 - science.org
INTRODUCTION Cadherins are an ancient class of transmembrane proteins that are
essential for the formation of multicellular tissues in metazoans. Cadherins link intercellular …

Organization and execution of the epithelial polarity programme

E Rodriguez-Boulan, IG Macara - Nature reviews Molecular cell biology, 2014 - nature.com
Epithelial cells require apical–basal plasma membrane polarity to carry out crucial vectorial
transport functions and cytoplasmic polarity to generate different cell progenies for tissue …

The many faces and functions of β‐catenin

T Valenta, G Hausmann, K Basler - The EMBO journal, 2012 - embopress.org
β‐Catenin (Armadillo in Drosophila) is a multitasking and evolutionary conserved molecule
that in metazoans exerts a crucial role in a multitude of developmental and homeostatic …

VE-cadherin and endothelial adherens junctions: active guardians of vascular integrity

M Giannotta, M Trani, E Dejana - Developmental cell, 2013 - cell.com
VE-cadherin is a component of endothelial cell-to-cell adherens junctions, and it has a key
role in the maintenance of vascular integrity. During embryo development, VE-cadherin is …

The role of mesenchymal–epithelial transition in endometrial function

A Owusu-Akyaw, K Krishnamoorthy… - Human reproduction …, 2019 - academic.oup.com
BACKGROUND The human uterine endometrium undergoes significant remodeling and
regeneration on a rapid and repeated basis, after parturition, menstruation, and in some …

Dynamic contacts: rearranging adherens junctions to drive epithelial remodelling

M Takeichi - Nature reviews Molecular cell biology, 2014 - nature.com
Epithelial cells display dynamic behaviours, such as rearrangement, movement and shape
changes, particularly during embryonic development and in equivalent processes in adults …