Intimate host attachment: enteropathogenic and enterohaemorrhagic Escherichia coli

YS Lai, I Rosenshine, JM Leong… - Cellular …, 2013 - Wiley Online Library
Enteropathogenic and enterohaemorrhagic E scherichia coli use a novel infection strategy
to colonize the gut epithelium, involving translocation of their own receptor, Tir, via a type III …

Adhesion of enteropathogenic Escherichia coli to host cells

JP Nougayrède, PJ Fernandes… - Cellular …, 2003 - Wiley Online Library
Enteropathogenic Escherichia coli (EPEC) adhere to the intestinal mucosa and to tissue
culture cells in a distinctive fashion, destroying microvilli, altering the cytoskeleton and …

Dissecting virulence: systematic and functional analyses of a pathogenicity island

W Deng, JL Puente, S Gruenheid, Y Li… - Proceedings of the …, 2004 - National Acad Sciences
Bacterial pathogenicity islands (PAI) often encode both effector molecules responsible for
disease and secretion systems that deliver these effectors to host cells. Human …

Enteropathogenic E. coli Tir binds Nck to initiate actin pedestal formation in host cells

S Gruenheid, R DeVinney, F Bladt, D Goosney… - Nature cell …, 2001 - nature.com
Enteropathogenic Escherichia coli (EPEC) is a bacterial pathogen that causes infantile
diarrhea worldwide. EPEC injects a bacterial protein, translocated intimin receptor (Tir), into …

Identification of the Secretion and Translocation Domain of the Enteropathogenic and Enterohemorrhagic Escherichia coli Effector Cif, Using TEM-1 β-Lactamase as …

X Charpentier, E Oswald - Journal of bacteriology, 2004 - Am Soc Microbiol
Enteropathogenic and enterohemorrhagic Escherichia coli (EPEC and EHEC) strains are
human and animal pathogens that inject effector proteins into host cells via a type III …

Locus of Enterocyte Effacement from Citrobacter rodentium: Sequence Analysis and Evidence for Horizontal Transfer among Attaching and Effacing Pathogens

W Deng, Y Li, BA Vallance, BB Finlay - Infection and immunity, 2001 - Am Soc Microbiol
The family of attaching and effacing (A/E) bacterial pathogens, which includes diarrheagenic
enteropathogenic Escherichia coli (EPEC) and enterohemorrhagic E. coli (EHEC), remains …

Host Susceptibility to the Attaching and Effacing Bacterial Pathogen Citrobacter rodentium

BA Vallance, W Deng, K Jacobson… - Infection and …, 2003 - Am Soc Microbiol
Many studies have shown that genetic susceptibility plays a key role in determining whether
bacterial pathogens successfully infect and cause disease in potential hosts. Surprisingly …

Enteropathogenic Escherichia coli EspF is targeted to mitochondria and is required to initiate the mitochondrial death pathway

JP Nougayrède, MS Donnenberg - Cellular microbiology, 2004 - Wiley Online Library
Enteropathogenic Escherichia coli (EPEC) is a causative agent of infant diarrhoea in
developing countries. The EspF protein is the product of the espF gene found on the locus of …

Citrobacter rodentium translocated intimin receptor (Tir) is an essential virulence factor needed for actin condensation, intestinal colonization and colonic hyperplasia …

W Deng, BA Vallance, Y Li, JL Puente… - Molecular …, 2003 - Wiley Online Library
Citrobacter rodentium infection of mice serves as a relevant small animal model to study
enterohaemorrhagic Escherichia coli (EHEC) and enteropathogenic E. coli (EPEC) …

Enteropathogenic and enterohaemorrhagic Escherichia coli deliver a novel effector called Cif, which blocks cell cycle G2/M transition

O Marchès, TN Ledger, M Boury, M Ohara… - Molecular …, 2003 - Wiley Online Library
Enteropathogenic Escherichia coli (EPEC) and enterohaemorrhagic E. coli (EHEC) are
closely related pathogens. Both use a type III secretion system (TTSS) encoded by the 'locus …