The role of the maternal immune system in reproductive success in humans remains
controversial. Here we focus on the events that occur in the maternal decidua during the first …

During pregnancy, semiallogeneic fetal extravillous trophoblasts (EVT) invade the uterine
mucosa without being rejected by the maternal immune system. Several mechanisms were …

HLA-G is a molecule that was first known to confer protection to the fetus from destruction by
the immune system of its mother, thus critically contributing to fetal–maternal tolerance. The …

The traditional way to study the immunology of pregnancy follows the classical
transplantation model, which views the fetus as an allograft. A more recent approach, which …

The genetic factors associated with susceptibility or resistance to viral infections are likely to
involve a sophisticated array of immune response. These genetic elements may modulate …

Natural killer (NK) cells have evolved to complement T and B cells in host defense against
pathogens and cancer. They recognize infected cells and tumors using a sophisticated array …

The HLA-G gene displays several peculiarities that are distinct from those of classical HLA
class I genes. The unique structure of the HLA-G molecule permits a restricted peptide …

Inhibitory leukocyte immunoglobulin-like receptors (LILRBs 1-5) transduce signals via
intracellular immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that recruit protein …

Malaria is among the most serious infectious diseases affecting humans, accounting for
approximately half a million deaths each year. Plasmodium falciparum causes most life …

Human leukocyte antigen G (HLA-G) is a nonclassic major histocompatibility complex
(MHC) class I molecule that functions as an immunomodulatory molecule capable of …