[HTML][HTML] pH sensitive hydrogels in drug delivery: Brief history, properties, swelling, and release mechanism, material selection and applications

M Rizwan, R Yahya, A Hassan, M Yar, AD Azzahari… - Polymers, 2017 - mdpi.com
Improving the safety efficacy ratio of existing drugs is a current challenge to be addressed
rather than the development of novel drugs which involve much expense and time. The …

Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems

M Karimi, A Ghasemi, PS Zangabad… - Chemical Society …, 2016 - pubs.rsc.org
New achievements in the realm of nanoscience and innovative techniques of nanomedicine
have moved micro/nanoparticles (MNPs) to the point of becoming actually useful for …

Temperature-responsive smart nanocarriers for delivery of therapeutic agents: applications and recent advances

M Karimi, P Sahandi Zangabad… - … applied materials & …, 2016 - ACS Publications
Smart drug delivery systems (DDSs) have attracted the attention of many scientists, as
carriers that can be stimulated by changes in environmental parameters such as …

Injectable hydrogels for sustained release of therapeutic agents

T Thambi, Y Li, DS Lee - Journal of Controlled Release, 2017 - Elsevier
Hydrogels are natural or synthetic polymer networks that exhibit high water absorbent
capacities and have been used as scaffolds for tissue engineering or as delivery carriers for …

In situ gelling pH-and temperature-sensitive biodegradable block copolymer hydrogels for drug delivery

NK Singh, DS Lee - Journal of Controlled Release, 2014 - Elsevier
Stimuli-sensitive injectable polymeric hydrogels have been extensively investigated during
the past decade as bioactive agent delivery vehicles and for tissue engineering applications …

Injectable polymeric hydrogels for the delivery of therapeutic agents: A review

QV Nguyen, JH Park, DS Lee - European Polymer Journal, 2015 - Elsevier
Since drug delivery systems have become one of the most promising areas of human health
related research, the applications of biomaterials such as hydrogels have been widely …

Metal-free photoinduced electron transfer–atom transfer radical polymerization (PET–ATRP) via a visible light organic photocatalyst

X Liu, L Zhang, Z Cheng, X Zhu - Polymer Chemistry, 2016 - pubs.rsc.org
The development of an atom transfer radical polymerization (ATRP) system without any
transition metal catalyst for electronic and biomedical applications was considered to be in …

Logic‐based delivery of site‐specifically modified proteins from environmentally responsive hydrogel biomaterials

PM Gawade, JA Shadish, BA Badeau… - Advanced …, 2019 - Wiley Online Library
The controlled presentation of proteins from and within materials remains of significant
interest for many bioengineering applications. Though “smart” platforms offer control over …

Recent strategies to develop pH-sensitive injectable hydrogels

T Thambi, JM Jung, DS Lee - Biomaterials Science, 2023 - pubs.rsc.org
“Smart” biomaterials that are responsive to pathological abnormalities are an appealing
class of therapeutic platforms for the development of personalized medications. The …

Recent trends in pH/thermo-responsive self-assembling hydrogels: from polyions to peptide-based polymeric gelators

C Chassenieux, C Tsitsilianis - Soft Matter, 2016 - pubs.rsc.org
In this article, we highlight some recent developments in “smart” physical hydrogels
achieved by self-assembling of block type macromolecules. More precisely we focus on two …