Regulated cell death is a major mechanism to eliminate damaged, infected, or superfluous
cells. Previously, apoptosis was thought to be the only regulated cell death mechanism; …

SARS-CoV is a pathogenic coronavirus that emerged from a zoonotic reservoir, leading to
global dissemination of the virus. The association SARS-CoV with aberrant cytokine …

The pathophysiology of COVID-19–associated thrombosis seems to be multifactorial. We
hypothesized that COVID-19 is accompanied by procoagulant platelets with subsequent …

Acute lung injury (ALI), a severe and life-threatening inflammation of the lung, with high
morbidity and mortality, underscoring the urgent need for novel treatments. Ge-Gen-Qin-Lian …

The ability of the lung to perform gas exchange is made possible in part by the effective
relationship between the alveolar epithelium and the endothelium of the pulmonary …

Pulmonary surfactant is a lipid/protein complex synthesized by the alveolar epithelium and
secreted into the airspaces, where it coats and protects the large respiratory air–liquid …

Acute lung injury (ALI) is still a leading cause of morbidity and mortality in critically ill
patients. Recently, our and other studies have found that hydrogen gas (H 2) treatment can …

Acute respiratory distress syndrome (ARDS) is an acute‐onset hypoxic condition with
radiographic bilateral lung infiltration. It is characterized by an acute exudative phase …

Highlights•The hCoVs induce inflammatory pneumonia, which in turn may cause ALI and
ARDS.•The inflammatory process may be caused by dysregulated uPA/uPAR …

The acute respiratory distress syndrome (ARDS) is an acute inflammatory process of the
lung caused by a direct or indirect insult to the alveolar-capillary membrane. Currently …