Protein aggregation–mechanisms, detection, and control

W Wang, CJ Roberts - International journal of pharmaceutics, 2018 - Elsevier
Protein aggregation has been recognized as one of the major challenges in the
development and commercialization of successful protein-based drug products because of …

Protein misfolding, aggregation and mechanism of amyloid cytotoxicity: An overview and therapeutic strategies to inhibit aggregation

M Zaman, AN Khan, SM Zakariya, RH Khan - International journal of …, 2019 - Elsevier
Protein and peptides are converted from their soluble forms into highly ordered fibrillar
aggregates under various conditions inside the cell. Such transitions confer diverse …

Effects of an electric field on the conformational transition of the protein: a molecular dynamics simulation study

Z Jiang, L You, W Dou, T Sun, P Xu - Polymers, 2019 - mdpi.com
The effect of the electric field on the conformational properties of the protein 1BBL was
investigated by molecular dynamics simulations. Our simulation results clearly capture the …

The potential of lactoferrin, ovotransferrin and lysozyme as antiviral and immune-modulating agents in COVID-19

JK Mann, T Ndung'u - Future Virology, 2020 - Taylor & Francis
Coronavirus disease 2019 (COVID-19), caused by SARS coronavirus 2 (SARS-CoV-2), is
spreading rapidly with no established effective treatments. While most cases are mild, others …

Lipase immobilization on synthesized hyaluronic acid-coated magnetic nanoparticle-functionalized graphene oxide composites as new biocatalysts: Improved …

V Atiroğlu - International journal of biological macromolecules, 2020 - Elsevier
Background Lipase is an enzyme that catalyzes the hydrolysis of lipids in watery and
organic interactions they can catalyze synthetic reactions, involving inter esterification …

The past and future of ovotransferrin: Physicochemical properties, assembly and applications

X Wang, Z Wei, C Xue - Trends in Food Science & Technology, 2021 - Elsevier
Background Ovotransferrin, a native protein with abundant nutritional value and various
functionalities, can be applied in numerous food systems. As the second most ample protein …

From enzyme stability to enzymatic bioelectrode stabilization processes

C Beaufils, HM Man, A de Poulpiquet, I Mazurenko… - Catalysts, 2021 - mdpi.com
Bioelectrocatalysis using redox enzymes appears as a sustainable way for biosensing,
electricity production, or biosynthesis of fine products. Despite advances in the knowledge of …

Stability issues and approaches to stabilised nanoparticles based drug delivery system

S Sultana, N Alzahrani, R Alzahrani… - Journal of drug …, 2020 - Taylor & Francis
Nanoparticles form the fundamental building blocks for many exciting applications in various
scientific disciplines due to its unique features such as large surface to mass ratio, targeting …

Various type immobilizations of Isocitrate dehydrogenases enzyme on hyaluronic acid modified magnetic nanoparticles as stable biocatalysts

LO Farhan, WA Mehdi, EM Taha, AM Farhan… - International Journal of …, 2021 - Elsevier
Magnetic nanoparticles (MNPs) were modified by hyaluronic acid (HA). After the process of
functionalization, two different strategies have been used to immobilize isocitrate …

Aggregation of irisin and its prevention by trehalose: A biophysical approach

R Waseem, D Yameen, T Khan, A Anwer… - Journal of Molecular …, 2023 - Elsevier
During the last two decades, protein misfolding and aggregation has become one of the
most competitive and challenging research problems, which underlies a broad range of …