Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes, with
several underlying pathophysiological mechanisms, some of which are still uncertain. The …

Neurotrophic Keratopathy (NK) refers to a condition where corneal epitheliopathy leading to
frank epithelial defect with or without stromal ulceration (melting) is associated with reduced …

With the global prevalence of diabetes mellitus over recent decades, more patients suffered
from various diabetic complications, including diabetic ocular surface diseases that may …

In the cornea, resident immune cells are in close proximity to sensory nerves, consistent with
their important roles in the maintenance of nerves in both homeostasis and inflammation …

The present study was set out to address the therapeutic efficacy of human adipose tissue
stem cells derived extracellular vesicles (hADSC-Evs) in a mouse model of dry eye disease …

Corneal nerves are instrumental to maintain cornea integrity through regulation of key
physiological functions such as tear secretion, blink reflex, and neuropeptide turnover …

The incidence of diabetes mellitus (DM) and its complications have increased considerably
worldwide. Diabetic keratopathy is the major complication of the cornea characterized by …

Diabetic keratopathy is characterized by impaired innervation of the cornea that leads to
decreased sensitivity, with resultant difficulties with epithelial wound healing. These …

The corneal epithelium is the first anatomical barrier between the environment and the
cornea; it is critical for proper light refraction onto the retina and prevents pathogens (eg …

Diabetic corneal neuropathy (DCN) is a common complication of diabetes. However, there
are very limited therapeutic options. We investigated the effects of a peroxisome proliferator …