High-resolution two-photon polymerization: The most versatile technique for the fabrication of microneedle arrays

Z Faraji Rad, PD Prewett, GJ Davies - Microsystems & nanoengineering, 2021 - nature.com
Microneedle patches have received much interest in the last two decades as drug/vaccine
delivery or fluid sampling systems for diagnostic and monitoring purposes. Microneedles are …

A comprehensive review of microneedles: Types, materials, processes, characterizations and applications

FK Aldawood, A Andar, S Desai - Polymers, 2021 - mdpi.com
Drug delivery through the skin offers many advantages such as avoidance of hepatic first-
pass metabolism, maintenance of steady plasma concentration, safety, and compliance over …

A microneedle vaccine printer for thermostable COVID-19 mRNA vaccines

A Vander Straeten, M Sarmadi, JL Daristotle… - Nature …, 2024 - nature.com
Decentralized manufacture of thermostable mRNA vaccines in a microneedle patch (MNP)
format could enhance vaccine access in low-resource communities by eliminating the need …

Microneedle for transdermal drug delivery: current trends and fabrication

JH Jung, SG Jin - Journal of pharmaceutical investigation, 2021 - Springer
Background Transdermal delivery has the advantage of bypassing the first-pass effect and
allowing sustained release of the drug. However, the drug delivery is limited owing to the …

The role of 3D printing technology in microengineering of microneedles

U Detamornrat, E McAlister, ARJ Hutton, E Larrañeta… - Small, 2022 - Wiley Online Library
Microneedles (MNs) are minimally invasive devices, which have gained extensive interest
over the past decades in various fields including drug delivery, disease diagnosis …

Hollow microneedles: A perspective in biomedical applications

Á Cárcamo-Martínez, B Mallon… - International journal of …, 2021 - Elsevier
Microneedles (MN) have the potential to become a highly progressive device for both drug
delivery and monitoring purposes as they penetrate the skin and pierce the stratum corneum …

3D-printed microneedles in biomedical applications

SR Dabbagh, MR Sarabi, R Rahbarghazi, E Sokullu… - Iscience, 2021 - cell.com
Conventional needle technologies can be advanced with emerging nano-and micro-
fabrication methods to fabricate microneedles. Nano-/micro-fabricated microneedles seek to …

Simple and customizable method for fabrication of high-aspect ratio microneedle molds using low-cost 3D printing

KJ Krieger, N Bertollo, M Dangol, JT Sheridan… - Microsystems & …, 2019 - nature.com
We present a simple and customizable microneedle mold fabrication technique using a low-
cost desktop SLA 3D printer. As opposed to conventional microneedle fabrication methods …

Microneedle-based natural polysaccharide for drug delivery systems (DDS): progress and challenges

F Damiri, N Kommineni, SO Ebhodaghe, R Bulusu… - Pharmaceuticals, 2022 - mdpi.com
In this focused progress review, the most widely accepted methods of transdermal drug
delivery are hypodermic needles, transdermal patches and topical creams. However …

Development and characterisation of novel poly (vinyl alcohol)/poly (vinyl pyrrolidone)-based hydrogel-forming microneedle arrays for enhanced and sustained …

IA Tekko, G Chen, J Domínguez-Robles… - International journal of …, 2020 - Elsevier
Methotrexate (MTX) is one of the mainstays of treatment for rheumatoid arthritis (RA) and
juvenile idiopathic arthritis (JIA) and it is mainly administered either orally or by …