Sex differences in neural mechanisms mediating reward and addiction

JB Becker, E Chartoff - Neuropsychopharmacology, 2019 - nature.com
There is increasing evidence in humans and laboratory animals for biologically based sex
differences in every phase of drug addiction: acute reinforcing effects, transition from …

The widespread regulation of microRNA biogenesis, function and decay

J Krol, I Loedige, W Filipowicz - Nature reviews genetics, 2010 - nature.com
MicroRNAs (miRNAs) are a large family of post-transcriptional regulators of gene expression
that are∼ 21 nucleotides in length and control many developmental and cellular processes …

[HTML][HTML] Translational control of long-lasting synaptic plasticity and memory

M Costa-Mattioli, WS Sossin, E Klann, N Sonenberg - Neuron, 2009 - cell.com
Long-lasting forms of synaptic plasticity and memory are dependent on new protein
synthesis. Recent advances obtained from genetic, physiological, pharmacological, and …

microRNAs at the synapse

G Schratt - Nature Reviews Neuroscience, 2009 - nature.com
MicroRNAs (miRNAs) are emerging as key modulators of post-transcriptional gene
regulation in a plethora of tissues, including the nervous system. Recent evidence points to …

Activity-dependent spatially localized miRNA maturation in neuronal dendrites

S Sambandan, G Akbalik, L Kochen, J Rinne… - Science, 2017 - science.org
MicroRNAs (miRNAs) regulate gene expression by binding to target messenger RNAs
(mRNAs) and preventing their translation. In general, the number of potential mRNA targets …

MicroRNA expression is down-regulated and reorganized in prefrontal cortex of depressed suicide subjects

NR Smalheiser, G Lugli, HS Rizavi, VI Torvik… - PloS one, 2012 - journals.plos.org
Background Recent studies suggest that alterations in expression of genes, including those
which regulate neural and structural plasticity, may be crucial in the pathogenesis of …

[HTML][HTML] The neurobiology of non-coding RNAs and Alzheimer's disease pathogenesis: Pathways, mechanisms and translational opportunities

E Lauretti, K Dabrowski, D Praticò - Ageing Research Reviews, 2021 - Elsevier
In the past two decades, advances in sequencing technology and analysis of the human and
mouse genome have led to the discovery of many non-protein-coding RNAs (ncRNAs) …

MicroRNA miR-137 regulates neuronal maturation by targeting ubiquitin ligase mind bomb-1

RD Smrt, KE Szulwach, RL Pfeiffer, X Li, W Guo… - Stem …, 2010 - academic.oup.com
The maturation of young neurons is regulated by complex mechanisms and dysregulation of
this process is frequently found in neurodevepmental disorders. MicroRNAs have been …

Circulating brain-enriched microRNAs as novel biomarkers for detection and differentiation of neurodegenerative diseases

KS Sheinerman, JB Toledo, VG Tsivinsky… - Alzheimer's research & …, 2017 - Springer
Background Minimally invasive specific biomarkers of neurodegenerative diseases (NDs)
would facilitate patient selection and disease progression monitoring. We describe the …

A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis

G Siegel, G Obernosterer, R Fiore, M Oehmen… - Nature cell …, 2009 - nature.com
The microRNA pathway has been implicated in the regulation of synaptic protein synthesis
and ultimately in dendritic spine morphogenesis, a phenomenon associated with long …