The bacterial phosphoenolpyruvate (PEP): carbohydrate phosphotransferase system (PTS)
carries out both catalytic and regulatory functions. It catalyzes the transport and …

The phosphoenolpyruvate (PEP): carbohydrate phosphotransferase system (PTS) is found
only in bacteria, where it catalyzes the transport and phosphorylation of numerous …

The limitations associated with natural enzyme catalysis have triggered the rise of the field of
protein engineering. Traditional rational design was based on the analysis of protein …

Carbon catabolite repression (CCR) in bacteria is generally regarded as a regulatory
mechanism to ensure sequential utilization of carbohydrates. Selection of the carbon …

Sequences and structures of all P-loop-fold proteins were compared with the aim of
reconstructing the principal events in the evolution of P-loop-containing kinases. It is shown …

Carbon catabolite repression (CCR) by transcriptional regulators follows different
mechanisms in gram-positive and gram-negative bacteria. In gram-positive bacteria, CcpA …

This article describes and reviews our efforts using Hex 3.1 to predict the docking modes of
the seven target protein–protein complexes presented in the CAPRI (Critical Assessment of …

Bacteria utilise carbon sources in a strictly controlled hierarchical manner for which they
have developed global control mechanisms that govern and coordinate carbon source …

Bacteria possess a repertoire of versatile protein kinases modulating diverse aspects of their
physiology by phosphorylating proteins on various amino acids including histidine, cysteine …

Kinases are a ubiquitous group of enzymes that catalyze the phosphoryl transfer reaction
from a phosphate donor (usually ATP) to a receptor substrate. Although all kinases catalyze …