Role of animal models in biomedical research: a review

P Mukherjee, S Roy, D Ghosh, SK Nandi - Laboratory Animal Research, 2022 - Springer
The animal model deals with the species other than the human, as it can imitate the disease
progression, its' diagnosis as well as a treatment similar to human. Discovery of a drug …

Large animal models in regenerative medicine and tissue engineering: to do or not to do

I Ribitsch, PM Baptista, A Lange-Consiglio… - … in Bioengineering and …, 2020 - frontiersin.org
Rapid developments in Regenerative Medicine and Tissue Engineering has witnessed an
increasing drive toward clinical translation of breakthrough technologies. However, the …

Application of collagen scaffold in tissue engineering: recent advances and new perspectives

C Dong, Y Lv - Polymers, 2016 - mdpi.com
Collagen is the main structural protein of most hard and soft tissues in animals and the
human body, which plays an important role in maintaining the biological and structural …

Evolution of biomimetic ECM scaffolds from decellularized tissue matrix for tissue engineering: A comprehensive review

Y Zhang, C Zhang, Y Li, L Zhou, N Dan, J Min… - International Journal of …, 2023 - Elsevier
Tissue engineering is essentially a technique for imitating nature. Natural tissues are made
up of three parts: extracellular matrix (ECM), signaling systems, and cells. Therefore …

Bioengineered human blood vessels

LE Niklason, JH Lawson - Science, 2020 - science.org
BACKGROUND Vascular replacement and repair for the treatment of atherosclerotic
disease, infection, and traumatic injury are some of the most commonly performed surgical …

[HTML][HTML] Biomaterial–related cell microenvironment in tissue engineering and regenerative medicine

J Gao, X Yu, X Wang, Y He, J Ding - Engineering, 2022 - Elsevier
An appropriate cell microenvironment is key to tissue engineering and regenerative
medicine. Revealing the factors that influence the cell microenvironment is a fundamental …

Tissue engineering at the blood‐contacting surface: A review of challenges and strategies in vascular graft development

D Radke, W Jia, D Sharma, K Fena… - Advanced …, 2018 - Wiley Online Library
Tissue engineered vascular grafts (TEVGs) are beginning to achieve clinical success and
hold promise as a source of grafting material when donor grafts are unsuitable or …

Biomaterial-driven in situ cardiovascular tissue engineering—a multi-disciplinary perspective

TB Wissing, V Bonito, CVC Bouten… - NPJ Regenerative …, 2017 - nature.com
There is a persistent and growing clinical need for readily-available substitutes for heart
valves and small-diameter blood vessels. In situ tissue engineering is emerging as a …

The effect of hypoxia-mimicking responses on improving the regeneration of artificial vascular grafts

M Rafique, T Wei, Q Sun, AC Midgley, Z Huang… - Biomaterials, 2021 - Elsevier
Cellular transition to hypoxia following tissue injury, has been shown to improve
angiogenesis and regeneration in multiple tissues. To take advantage of this, many hypoxia …

Tissue-engineered small diameter arterial vascular grafts from cell-free nanofiber PCL/chitosan scaffolds in a sheep model

T Fukunishi, CA Best, T Sugiura, T Shoji, T Yi… - PLoS one, 2016 - journals.plos.org
Tissue engineered vascular grafts (TEVGs) have the potential to overcome the issues faced
by existing small diameter prosthetic grafts by providing a biodegradable scaffold where the …