The mammalian lung´ s structural design is optimized to serve its main function: gas
exchange. It takes place in the alveolar region (parenchyma) where air and blood are …

Osteosarcoma is the most common primary bone malignancy in adolescents. Its high
propensity to metastasize is the leading cause for treatment failure and poor prognosis …

Stem cells undergo dynamic changes in response to injury to regenerate lost cells.
However, the identity of transitional states and the mechanisms that drive their trajectories …

The main function of the lungs is oxygen transport from the atmosphere into the blood
circulation, while it is necessary to keep the pulmonary tissue relatively free of pathogens …

Elastin is expressed in most tissues that require elastic recoil. The protein first appeared
coincident with the closed circulatory system, and was critical for the evolutionary success of …

Organ regeneration requires dynamic cell interactions to reestablish cell numbers and tissue
architecture. While we know the identity of progenitor cells that replace lost tissue, the …

This review analyses the mechanisms by which lung fluid balance is strictly controlled in the
air-blood barrier (ABB). Relatively large trans-endothelial and trans-epithelial Starling …

Carbonic anhydrases (CAs) catalyze a reaction fundamental for life: the bidirectional
conversion of carbon dioxide (CO2) and water (H2O) into bicarbonate (HCO3−) and protons …

An overview of the application of natural and synthetic, non-viral vectors for oligonucleotide
delivery into the lung is presented in this review, with a special focus on lung cancer. Due to …

The dynamics of respiratory airflows and the associated transport mechanisms of inhaled
aerosols characteristic of the deep regions of the lungs are of broad interest in assessing …