Candida albicans cell-type switching and functional plasticity in the mammalian host
SM Noble, BA Gianetti, JN Witchley - Nature Reviews Microbiology, 2017 - nature.com
Candida albicans is a ubiquitous commensal of the mammalian microbiome and the most
prevalent fungal pathogen of humans. A cell-type transition between yeast and hyphal …
prevalent fungal pathogen of humans. A cell-type transition between yeast and hyphal …
Growth of Candida albicans hyphae
PE Sudbery - Nature Reviews Microbiology, 2011 - nature.com
The fungus Candida albicans is often a benign member of the mucosal flora; however, it
commonly causes mucosal disease with substantial morbidity and in vulnerable patients it …
commonly causes mucosal disease with substantial morbidity and in vulnerable patients it …
Interaction of Candida albicans with host cells: virulence factors, host defense, escape strategies, and the microbiota
S Höfs, S Mogavero, B Hube - Journal of microbiology, 2016 - Springer
The interaction between Candida albicans and its host cells is characterized by a complex
interplay between the expression of fungal virulence factors, which results in adherence …
interplay between the expression of fungal virulence factors, which results in adherence …
Nonfilamentous C. albicans mutants are avirulent
HJ Lo, JR Köhler, B DiDomenico, D Loebenberg… - Cell, 1997 - cell.com
Candida albicans and Saccharomyces cerevisiae switch from a yeast to a filamentous form.
In Saccharomyces, this switch is controlled by two regulatory proteins, Ste12p and Phd1p …
In Saccharomyces, this switch is controlled by two regulatory proteins, Ste12p and Phd1p …
Regulatory circuitry governing fungal development, drug resistance, and disease
Pathogenic fungi have become a leading cause of human mortality due to the increasing
frequency of fungal infections in immunocompromised populations and the limited …
frequency of fungal infections in immunocompromised populations and the limited …
Transcriptional Response of Candida albicans upon Internalization by Macrophages
MC Lorenz, JA Bender, GR Fink - Eukaryotic cell, 2004 - Am Soc Microbiol
The opportunistic fungal pathogen Candida albicans is both a benign gut commensal and a
frequently fatal systemic pathogen. The interaction of C. albicans with the host's innate …
frequently fatal systemic pathogen. The interaction of C. albicans with the host's innate …
Candida albicans: A molecular revolution built on lessons from budding yeast
J Berman, PE Sudbery - Nature Reviews Genetics, 2002 - nature.com
Candida albicans is an opportunistic fungal pathogen that is found in the normal
gastrointestinal flora of most healthy humans. However, in immunocompromised patients …
gastrointestinal flora of most healthy humans. However, in immunocompromised patients …
Signal transduction cascades regulating fungal development and virulence
KB Lengeler, RC Davidson, C D'souza… - Microbiology and …, 2000 - Am Soc Microbiol
Cellular differentiation, mating, and filamentous growth are regulated in many fungi by
environmental and nutritional signals. For example, in response to nitrogen limitation …
environmental and nutritional signals. For example, in response to nitrogen limitation …
Environmental Sensing and Signal Transduction Pathways Regulating Morphopathogenic Determinants of Candida albicans
Candida albicans is an opportunistic fungal pathogen that is found in the normal
gastrointestinal flora of most healthy humans. However, under certain environmental …
gastrointestinal flora of most healthy humans. However, under certain environmental …
White-opaque switching in Candida albicans is controlled by mating-type locus homeodomain proteins and allows efficient mating
MG Miller, AD Johnson - Cell, 2002 - cell.com
Discovered over a decade ago, white-opaque switching in the human fungal pathogen
Candida albicans is an alternation between two quasistable, heritable transcriptional states …
Candida albicans is an alternation between two quasistable, heritable transcriptional states …