Brain, the major organ of the central nervous system controls and processes most of body
activities. Therefore, the most aggressive brain tumor–glioblastoma and metastases from …

AD is a progressive neurodegenerative disorder and a leading cause of dementia in an
aging population worldwide. The enormous challenge which AD possesses to global …

Cancer is one of the major and leading causes of death worldwide. Two of the greatest
challenges in fighting cancer are early detection and effective treatments with no or …

Introduction: Over the past decade, several library-based methods have been developed to
discover ligands with strong binding affinities for their targets. These methods mimic the …

Graphical Abstract Abstract Alterations in the homeostasis of several adhesion GPCRs
(aGPCRs) have been observed in cancer. The main cellular functions regulated by aGPCRs …

Tumorigenesis is a multistep process, during which cells acquire a series of mutations that
lead to unrestrained cell growth and proliferation, inhibition of cell differentiation, and …

Cancer is one of the leading causes of mortality worldwide; nearly 10 million people died
from it in 2020. The high mortality rate results from the lack of effective screening …

Abstract The World Health Organization has designated Staphylococcus aureus as a global
health concern. This designation stems from the emergence of multiple drug‐resistant …

Glioma is a life-threatening malignant tumor. Resistance to traditional treatments and tumor
recurrence present major challenges in treating and managing this disease, consequently …

A mutation in the isocitrate dehydrogenase 1 (IDH1) gene is the most common mutation in
diffuse lower-grade gliomas (LGGs), and it is significantly related to the prognosis of LGGs …