Comprehensive overview and assessment of computational prediction of microRNA targets in animals

X Fan, L Kurgan - Briefings in bioinformatics, 2015 - academic.oup.com
MicroRNAs (miRNAs) are short endogenous noncoding RNAs that bind to target mRNAs,
usually resulting in degradation and translational repression. Identification of miRNA targets …

Plasticity of mitochondrial translation

S Dennerlein, C Wang, P Rehling - Trends in Cell Biology, 2017 - cell.com
Mitochondria maintained a genome during evolution to synthesize core subunits of the
oxidative phosphorylation system. Expression of the mitochondrial genome requires …

miRPathDB: a new dictionary on microRNAs and target pathways

C Backes, T Kehl, D Stöckel, T Fehlmann… - Nucleic acids …, 2016 - academic.oup.com
In the last decade, miRNAs and their regulatory mechanisms have been intensively studied
and many tools for the analysis of miRNAs and their targets have been developed. We …

miR-15a inhibits cell proliferation and epithelial to mesenchymal transition in pancreatic ductal adenocarcinoma by down-regulating Bmi-1 expression

S Guo, X Xu, Y Tang, C Zhang, J Li, Y Ouyang, J Ju… - Cancer letters, 2014 - Elsevier
Purposes To investigate whether miR-15a inhibits cell proliferation and epithelial–
mesenchymal transition (EMT) in pancreatic ductal adenocarcinoma (PDAC) via the down …

CircRNF111 protects against insulin resistance and lipid deposition via regulating miR-143-3p/IGF2R axis in metabolic syndrome

X Lin, Y Du, W Lu, W Gui, S Sun, Y Zhu… - Frontiers in Cell and …, 2021 - frontiersin.org
Abnormal expression of circRNAs (circular RNAs), a subclass of non-coding RNAs, has
been documented in numerous human diseases. Herein, we explored whether circRNAs act …

MiR‐154 directly suppresses DKK2 to activate Wnt signaling pathway and enhance activation of cardiac fibroblasts

LY Sun, ZD Bie, CH Zhang, H Li, LD Li… - Cell Biology …, 2016 - Wiley Online Library
Excessive proliferation of cardiac fibroblasts (CFs) and their transdifferentiation into
myofibroblasts leads to expression of α‐smooth muscle actin (α‐SMA), as well as excessive …

[HTML][HTML] mir-21 在食管鳞癌中的表达及其与临床病理行为的关系

赵俊刚, 任开明, 汤隽, 张磊 - 世界华人消化杂志, 2012 - wjgnet.com
mir-21在食管鳞癌中的表达及其与临床病理行为的关系 主页 简体中文 English 简体中文 登录
BPG Management System F6Publishing-Submit a Manuscript F6Publishing-世界华人消化杂志 …

Systems Biology Approaches in the Design of Effective miRNA-Targeted Therapeutics

RM Mohammad, B Bao, FH Sarkar, PA Philip… - MicroRNA Targeted …, 2014 - Springer
MicroRNAs (miRNAs) are short non-coding RNAs that are recognized to epigenetically
modulate gene expression by weakly binding to the 3′ UTR and/or other sites of target …

Modulation of Expression of miRNAs for Therapeutic Effects in Human Malignant Neuroblastoma

SK Ray - Neuroblastoma, 2019 - Elsevier
The small non-coding RNAs are called microRNAs or miRNAs that play key roles in mRNA
silencing as well as in post-transcriptional regulation of gene expression in eukaryotic cells …

Integrative genomic approaches towards nuclear receptors and their regulators in cancer

MD Long - 2016 - search.proquest.com
Nuclear receptors (NRs) comprise a superfamily of ligand activated transcription factors
which are integral to normal development and physiology in animals. As such, disruptions to …