Aging of the vestibular system and its relationship to dementia

PF Smith - Current opinion in neurology, 2024 - journals.lww.com
The conclusion of these recent studies is that, consistent with previous studies, vestibular
function declines with age, and that this age-related decline is associated with cognitive …

[HTML][HTML] Overestimation in angular path integration precedes Alzheimer's dementia

A Castegnaro, Z Ji, K Rudzka, D Chan, N Burgess - Current Biology, 2023 - cell.com
Path integration (PI) is impaired early in Alzheimer's disease (AD) but reflects multiple sub-
processes that may be differentially sensitive to AD. To characterize these sub-processes …

Spatial orientation, postural control and the vestibular system in healthy elderly and alzheimer's dementia

MK Chepisheva - PeerJ, 2023 - peerj.com
Background While extensive research has been advancing our understanding of the spatial
and postural decline in healthy elderly (HE) and Alzheimer's disease (AD), much less is …

Association of Alzheimer's Disease With Peripheral Vestibular Disorder: A Case–Control Study

SH Hung, S Xirasagar, YF Cheng, HC Lin… - The …, 2024 - Wiley Online Library
Objectives Vestibular disorders can impact cognitive domains, including spatial orientation
and memory, which are also affected in Alzheimer's disease. This study aimed to examine …

Modeling the impact of genotype, age, sex, and continuous navigation on pathway integration performance

D Pink, E Ilkel, V Chandreswaran, D Moser… - BioRxiv, 2023 - biorxiv.org
Abstract The Path Integration (PI) task stands as a fundamental activity within spatial
navigation, encompassing a multifaceted underlying process that requires extensive …

The importance of the vestibular system in Alzheimer's disease

ZH Dastgerdi, B Khavarghazalani - NPG Neurologie-Psychiatrie-Gériatrie, 2024 - Elsevier
Population aging is an irreversible and increasing global trend. Many disorders occur with
aging. One of the common disorders is the occurrence of dementia and Alzheimer's (AD) …

[PDF][PDF] A Cognitive-Motor Framework of Spatial Navigation in Aging and Alzheimer's Disease

P Hill, A Ekstrom - osf.io
Spatial navigation is essential for wellbeing and independence and shows significant
declines as part of age-related neurodegenerative disorders, such as Alzheimer's disease …