Allergic rhinitis is a symptomatic disorder of the nose induced after allergen exposure by an
immunoglobulin E (IgE)-mediated inflammation of the membranes lining the nose (1). It was …

The three main soil-transmitted helminth infections, ascariasis, trichuriasis, and hookworm,
are common clinical disorders in man. The gastrointestinal tract of a child living in poverty in …

Helminths have evolved to become experts at subverting immune surveillance. Through
potent and persistent immune tempering, helminths can remain undetected in human …

Despite its well‐known association with IgE‐mediated allergy, IgG4 antibodies still have
several poorly understood characteristics. IgG4 is a very dynamic antibody: the antibody is …

The increase of allergic diseases in the industrialized world has often been explained by a
decline in infections during childhood. The immunological explanation has been put into the …

Immunology was founded by studying the body's response to infectious microorganisms,
and yet microbial prokaryotes only tell half the story of the immune system. Eukaryotic …

BACKGROUND: Oral immunotherapy (OIT) has been thought to induce clinical
desensitization to allergenic foods, but trials coupling the clinical response and immunologic …

Immune regulation by parasites is a global concept that includes suppression, diversion,
and conversion of the host immune response to the benefit of the pathogen. While many …

Rising rates of allergic disease accompany the healthier benefits of a contemporary
westernized lifestyle, such as low infant mortality. It is likely that these twinned phenomena …

Schistosome infections are characterized by prominent T cell hyporesponsiveness during
the chronic stage of infection. We found that schistosome-specific phosphatidylserine (PS) …