Therapeutic interventions after spinal cord injury
Spinal cord injury (SCI) can lead to paraplegia or quadriplegia. Although there are no fully
restorative treatments for SCI, various rehabilitative, cellular and molecular therapies have …
restorative treatments for SCI, various rehabilitative, cellular and molecular therapies have …
Formaldehyde exposure and leukemia: a new meta-analysis and potential mechanisms
Formaldehyde is an economically important chemical, to which more than 2 million US
workers are occupationally exposed. Substantially more people are exposed to …
workers are occupationally exposed. Substantially more people are exposed to …
Autologous olfactory ensheathing cell transplantation in human paraplegia: a 3-year clinical trial
A Mackay-Sim, F Feron, J Cochrane… - Brain, 2008 - academic.oup.com
Olfactory ensheathing cells show promise in preclinical animal models as a cell
transplantation therapy for repair of the injured spinal cord. This is a report of a clinical trial of …
transplantation therapy for repair of the injured spinal cord. This is a report of a clinical trial of …
Olfactory mucosa autografts in human spinal cord injury: a pilot clinical study
C Lima, J Pratas-Vital, P Escada… - The journal of spinal …, 2006 - Taylor & Francis
Abstract Background/Objective: Olfactory mucosa is a readily accessible source of olfactory
ensheathing and stem-like progenitor cells for neural repair. To determine the safety and …
ensheathing and stem-like progenitor cells for neural repair. To determine the safety and …
EdU, a new thymidine analogue for labelling proliferating cells in the nervous system
F Chehrehasa, ACB Meedeniya, P Dwyer… - Journal of neuroscience …, 2009 - Elsevier
Labelling and identifying proliferating cells is central to understanding neurogenesis and
neural lineages in vivo and in vitro. We present here a novel thymidine analogue, ethynyl …
neural lineages in vivo and in vitro. We present here a novel thymidine analogue, ethynyl …
The human nose harbors a niche of olfactory ectomesenchymal stem cells displaying neurogenic and osteogenic properties
B Delorme, E Nivet, J Gaillard, T Häupl… - Stem cells and …, 2010 - liebertpub.com
We previously identified multipotent stem cells within the lamina propria of the human
olfactory mucosa, located in the nasal cavity. We also demonstrated that this cell type …
olfactory mucosa, located in the nasal cavity. We also demonstrated that this cell type …
Olfactory mucosal autografts and rehabilitation for chronic traumatic spinal cord injury
C Lima, P Escada, J Pratas-Vital… - … and neural repair, 2010 - journals.sagepub.com
Background/objective. Basic science advances in spinal cord injury (SCI) are leading to
novel clinical approaches. The authors report a prospective, uncontrolled pilot study of the …
novel clinical approaches. The authors report a prospective, uncontrolled pilot study of the …
Lineage-specific distribution of high levels of genomic
A Ruzov, Y Tsenkina, A Serio, T Dudnakova, J Fletcher… - Cell research, 2011 - nature.com
Methylation of cytosine is a DNA modification associated with gene repression. Recently, a
novel cytosine modification, 5-hydroxymethylcytosine (5-hmC) has been discovered. Here …
novel cytosine modification, 5-hydroxymethylcytosine (5-hmC) has been discovered. Here …
Disease-specific, neurosphere-derived cells as models for brain disorders
N Matigian, G Abrahamsen… - Disease models & …, 2010 - journals.biologists.com
There is a pressing need for patient-derived cell models of brain diseases that are relevant
and robust enough to produce the large quantities of cells required for molecular and …
and robust enough to produce the large quantities of cells required for molecular and …
Parkinson's disease-associated human ATP13A2 (PARK9) deficiency causes zinc dyshomeostasis and mitochondrial dysfunction
JS Park, B Koentjoro, D Veivers… - Human molecular …, 2014 - academic.oup.com
Abstract Human ATP13A2 (PARK9), a lysosomal type 5 P-type ATPase, has been
associated with autosomal recessive early-onset Parkinson's disease (PD). ATP13A2 …
associated with autosomal recessive early-onset Parkinson's disease (PD). ATP13A2 …