Zoledronic acid (ZA) has been shown to be beneficial against cancer both directly and
indirectly. However, because of its fast absorption by bone, its use in extraskeletal …

Antibiotics are considered one of the great “miracles” of the 20th century. Now in the 21st
century in the post-antibiotic era, the miracle is turning into a nightmare, due to the growing …

For topical treatment of skin cancer, the design of pH-responsive nanocarriers able to
selectively release the drug in the tumor acidic microenvironment represents a reliable …

The preparation and characterization of ionic liquids and organic salts (OSILs) that contain
anionic penicillin G [secoPen] and amoxicillin [seco-Amx] hydrolysate derivatives and their …

As the development of novel antibiotics has been at a halt for several decades, chemically
enhancing existing drugs is a very promising approach to drug development. Herein, we …

The combination of active pharmaceutical ingredients in the form of ionic liquids or organic
salts (API-OSILs) with mesoporous silica nanoparticles (MSNs) as drug carriers can provide …

As the existing therapeutic modalities for the treatment of cryptococcal meningitis (CM) have
suboptimal efficacy, repurposing existing drugs for the treatment of CM is of great interest …

Herein the quantitative synthesis of eight new mono-and dianionic Organic Salts and Ionic
Liquids (OSILs) from alendronic acid (ALN) is reported by following two distinct sustainable …

The development of effective antiviral drugs against SARS-CoV-2 is urgently needed and a
global health priority. In light of the initial data regarding the repurposing of …

Tuberculosis is one of the ten causes of morbidity and mortality worldwide caused by
Mycobacterium tuberculosis complex. Some of the anti-tuberculosis drugs used in clinic …