Extracellular vesicles (EVs) have emerged as promising candidates for multiple biomedical
applications. Major types of EVs include exosomes, microvesicles, and apoptotic bodies …

During the past decades, anticancer immunotherapy has evolved from a promising
therapeutic option to a robust clinical reality. Many immunotherapeutic regimens are now …

Apoptosis, a form of programmed cell death, is essential for growth and tissue homeostasis.
Apoptotic bodies (ApoBDs) are a form of extracellular vesicles (EVs) released by dying cells …

Dendritic-cells (DCs) have received considerable attention as potential targets for the
development of anticancer vaccines. DC-based anticancer vaccination relies on patient …

Background The last decade witnessed the emergence of several therapeutic options for
patients with chronic lymphocytic leukemia (CLL) for first-line and relapsed settings. The vast …

Extracellular vesicles (EVs) are membrane-bound particles released by cells in various
(patho) physiological conditions. EVs can transfer effector molecules and elicit potent …

Dendritic cells (DCs) are versatile elements of the immune system and are best known for
their unparalleled ability to initiate and modulate adaptive immune responses. During the …

Extracellular vesicles (EVs), membrane-bound vesicles that are naturally released by cells,
have emerged as new therapeutic opportunities. EVs, particularly exosomes and …

Dendritic cell (DC)-based vaccines against cancer have been extensively developed over
the past two decades. Typically DC-based cancer immunotherapy entails loading patient …

Evidence for the existence of CLL-specific antigens recognized by the immune system can
be gathered from the observation that many patients display monoclonal or oligoclonal …