Non-coding RNAs in human health and disease: potential function as biomarkers and therapeutic targets

T Loganathan, GP Doss C - Functional & integrative genomics, 2023 - Springer
Human diseases have been a critical threat from the beginning of human history. Knowing
the origin, course of action and treatment of any disease state is essential. A microscopic …

The role of apoptosis in the pathogenesis of osteoarthritis

SQ Xiao, M Cheng, L Wang, J Cao, L Fang… - International …, 2023 - Springer
Purpose Apoptosis is an important physiological process, making a great difference to
development and tissue homeostasis. Osteoarthritis (OA) is a chronic joint disease …

Exploring the feasibility of circulating miRNAs as diagnostic and prognostic biomarkers in osteoarthritis: Challenges and opportunities

K Felekkis, M Pieri, C Papaneophytou - International Journal of Molecular …, 2023 - mdpi.com
Osteoarthritis (OA) is a prevalent degenerative joint disease characterized by progressive
cartilage degradation and joint inflammation. As the most common aging-related joint …

[HTML][HTML] Biomaterial-based scaffolds in promotion of cartilage regeneration: Recent advances and emerging applications

J Liang, P Liu, X Yang, L Liu, Y Zhang, Q Wang… - Journal of Orthopaedic …, 2023 - Elsevier
Osteoarthritis (OA) poses a significant burden for countless individuals, inflicting relentless
pain and impairing their quality of life. Although traditional treatments for OA focus on pain …

Pseudogenes in cancer: state of the art

AK Nakamura-García, J Espinal-Enríquez - Cancers, 2023 - mdpi.com
Simple Summary Out of the billions of nucleotides comprising the human DNA, a substantial
proportion (98%) represents non-coding DNA, meaning DNA that is not translated into …

Identification and comprehensive analysis of circRNA–miRNA–mRNA regulatory networks in osteoarthritis

X Liu, H Xiao, X Peng, Y Chai, S Wang… - Frontiers in …, 2023 - frontiersin.org
Osteoarthritis (OA) is a common orthopedic degenerative disease, leading to high disability
in activities of daily living. There remains an urgent need to identify the underlying …

LncRNA WDR11-AS1 promotes extracellular matrix synthesis in osteoarthritis by directly interacting with RNA-binding protein PABPC1 to stabilize SOX9 expression

H Huang, J Yan, X Lan, Y Guo, M Sun, Y Zhao… - International Journal of …, 2023 - mdpi.com
Osteoarthritis (OA) is a degenerative disease of articular cartilage that is mainly
characterized by chronic and mild inflammation of the joints. Recently, many studies have …

[HTML][HTML] Osteoarthritis year in review 2022: Genetics, genomics and epigenetics

M Kim, A Rubab, WCW Chan, D Chan - Osteoarthritis and Cartilage, 2023 - Elsevier
This “year in review” provides a summary of the research findings on the topic of genetics,
genomics and epigenetics for osteoarthritis (OA) between Mar 2021–Apr 2022. A search …

Emerging role of lncRNAs in osteoarthritis: An updated review

R Wang, HT Shiu, WYW Lee - Frontiers in immunology, 2022 - frontiersin.org
Osteoarthritis (OA) is a prevalent joint disease, which is associated with progressive articular
cartilage loss, synovial inflammation, subchondral sclerosis and meniscus injury. The …

The impact of non-coding RNAs in the pathobiology of eye disorders

LM Rad, MM Sadoughi, A Nicknam, AH Colagar… - International journal of …, 2023 - Elsevier
Eye disorders are common disorders with significant effects on personal, economic, and
social aspects of life. These disorders have a genetic background and are associated with …