The encephalomyocarditis virus (EMCV) is a small non-enveloped single-strand RNA virus,
the causative agent of not only myocarditis and encephalitis, but also neurological diseases …

Theiler's murine encephalomyelitis virus (TMEV) infection of mice is an experimental model
for multiple sclerosis (MS). TMEV induces a biphasic disease in susceptible mouse strains …

Virus infection can initiate a type I interferon (IFN-α/β) response via activation of the cytosolic
RNA sensors retinoic acid-inducible gene-I (RIG-I) and melanoma differentiation-associated …

The compartmentalization of DNA replication and gene transcription in the nucleus and
protein production in the cytoplasm is a defining feature of eukaryotic cells. The nucleus …

Stress granules (SG) are cytoplasmic aggregates of stalled translation preinitiation
complexes that form in cells exposed to various environmental stresses. Here, we show that …

Viral hemorrhagic septicemia virus (VHSV) and infectious hematopoietic necrosis virus
(IHNV) are members of the genus Novirhabdovirus within the Rhabdoviridae family, which …

A long-standing paradigm in virology was that non-enveloped viruses induce cell lysis to
release progeny virions. However, emerging evidence indicates that some non-enveloped …

West Nile virus (WNV) is a mosquito-transmitted pathogen that can cause serious disease in
humans. Our laboratories are focused on understanding how interactions between WNV …

Interactions with host defences are key aspects of viral infection. Various viral proteins
perform counter-defensive functions, but a distinct class, called security proteins, is …

Porcine epidemic diarrhea virus (PEDV) replicates in the cytoplasm of infected cells, but its
nucleocapsid (N) protein localizes specifically to the nucleolus. The mechanism of nuclear …