The “very old intensive care patients”(abbreviated to VOPs; greater than 80 years old) are
probably the fastest expanding subgroup of all intensive care unit (ICU) patients. Up until …

Since the discovery and definition of neutrophil extracellular traps (NETs) 14 years ago,
numerous characteristics and physiological functions of NETs have been uncovered …

Autophagy is an evolutionarily conserved intracellular degradation system aiming to
maintain cell homeostasis in response to cellular stress. At physiological states, basal or …

Formation of neutrophil extracellular traps (NET s) is an important function of the innate
immune system against infections. It has been proven that aging dysregulates immunity and …

In addition to their well-known role as the cellular mediators of immunity, key other roles
have been identified for neutrophils during septic shock. Importantly, neutrophils indeed play …

Sepsis represents the host's systemic inflammatory response to an infection. In this
condition, immune response associates a marked inflammatory response and the delayed …

" Science means constantly walking a tight rope" Heinrich Rohrer, physicist, 1933.
Community-acquired pneumonia (CAP) is the leading cause of death from infectious …

Septic shock is a life‐threatening clinical condition characterized by a robust immune
inflammatory response to disseminated infection. Little is known about its impact on the …

Objective To screen out core genes potentially prognostic for sepsis and construct a
competing endogenous RNA (ceRNA) regulatory network. Methods Subjects included in this …

Purpose To screen biomarkers in the serum of patients with sepsis by proteomics combined
with RNA sequencing technology, and to find new diagnostic and therapeutic targets for …