This paper discusses the problems associated with nasal drug delivery and how it is
possible, sometimes by means of quite simple concepts, to improve transport across the …

A variety of different types of nasal vaccine systems has been described to include cholera
toxin, microspheres, nanoparticles, liposomes, attenuated virus and cells and outer …

Nasal drug delivery has now been recognized as a very promising route for delivery of
therapeutic compounds including biopharmaceuticals. It has been demonstrated that low …

The respiratory tract mucosa is not only the site of infection for influenza viruses but also the
site of defense against virus infection. Viruses are initially detected and destroyed non …

OBJECTIVE: We studied the coadjuvant capability of oral consumption of the breast-milk–
isolated strain Lactobacillus fermentum (CECT5716) for an anti-influenza vaccine …

Influenza poses a severe threat to global health. Despite the whole inactivated virus (WIV)‐
based nasal vaccine being a promising strategy for influenza protection, the mucosal barrier …

The role of secretory IgA in conferring cross-protective immunity was examined in polymeric
(p) IgR knockout (KO) mice immunized intranasally with different inactivated vaccines …

Mice recovered from influenza A virus infection have been shown to be cross-protected
against challenge infection with either drift viruses within a subtype (subtype-specific …

Respiratory syncytial virus (RSV) infection is often associated in infancy with life-threatening
bronchiolitis, which is also a major risk factor for the development of asthma. At present, no …

Components of bacteria have been shown to induce innate antiviral immunity via Toll-like
receptors (TLRs). We have recently shown that FimH, the adhesin portion of type 1 fimbria …