The human phenotype ontology
PN Robinson, S Mundlos - Clinical genetics, 2010 - Wiley Online Library
Robinson PN, Mundlos S. The Human Phenotype Ontology. A standardized, controlled
vocabulary allows phenotypic information to be described in an unambiguous fashion in …
vocabulary allows phenotypic information to be described in an unambiguous fashion in …
Understanding the role of ETS-mediated gene regulation in complex biological processes
VJ Findlay, AC LaRue, DP Turner, PM Watson… - Advances in cancer …, 2013 - Elsevier
Ets factors are members of one of the largest families of evolutionarily conserved
transcription factors, regulating critical functions in normal cell homeostasis, which when …
transcription factors, regulating critical functions in normal cell homeostasis, which when …
SAM pointed domain ETS factor (SPDEF) regulates terminal differentiation and maturation of intestinal goblet cells
TK Noah, A Kazanjian, J Whitsett, NF Shroyer - Experimental cell research, 2010 - Elsevier
Background and Aims: SPDEF (also termed PDEF or PSE) is an ETS family transcription
factor that regulates gene expression in the prostate and goblet cell hyperplasia in the lung …
factor that regulates gene expression in the prostate and goblet cell hyperplasia in the lung …
Gene signature driving invasive mucinous adenocarcinoma of the lung
M Guo, K Tomoshige, M Meister, T Muley… - EMBO molecular …, 2017 - embopress.org
Though invasive mucinous adenocarcinoma of the lung (IMA) is pathologically distinctive,
the molecular mechanism driving IMA is not well understood, which hampers efforts to …
the molecular mechanism driving IMA is not well understood, which hampers efforts to …
[HTML][HTML] An update on the LIM and SH3 domain protein 1 (LASP1): a versatile structural, signaling, and biomarker protein
MF Orth, A Cazes, E Butt, TGP Grunewald - Oncotarget, 2015 - ncbi.nlm.nih.gov
The gene encoding the LIM and SH3 domain protein (LASP1) was cloned two decades ago
from a cDNA library of breast cancer metastases. As the first protein of a class comprising …
from a cDNA library of breast cancer metastases. As the first protein of a class comprising …
Role of LIM and SH3 protein 1 (LASP1) in the metastatic dissemination of medulloblastoma
C Traenka, M Remke, A Korshunov, S Bender… - Cancer research, 2010 - AACR
Medulloblastoma is the most common malignant pediatric brain tumor and is one of the
leading causes of cancer-related mortality in children. Treatment failure mainly occurs in …
leading causes of cancer-related mortality in children. Treatment failure mainly occurs in …
SPDEF functions as a colorectal tumor suppressor by inhibiting β-catenin activity
BACKGROUND & AIMS: Expression of the SAM pointed domain containing ETS
transcription factor (SPDEF or prostate-derived ETS factor) is regulated by Atoh1 and is …
transcription factor (SPDEF or prostate-derived ETS factor) is regulated by Atoh1 and is …
[HTML][HTML] FLI1 expression is correlated with breast cancer cellular growth, migration, and invasion and altered gene expression
MN Scheiber, PM Watson, T Rumboldt, C Stanley… - Neoplasia, 2014 - Elsevier
ETS factors have been shown to be dysregulated in breast cancer. ETS factors control the
expression of genes involved in many biological processes, such as cellular proliferation …
expression of genes involved in many biological processes, such as cellular proliferation …
Upregulation of prostate‐derived Ets factor by luteolin causes inhibition of cell proliferation and cell invasion in prostate carcinoma cells
KH Tsui, LC Chung, TH Feng… - … Journal of Cancer, 2012 - Wiley Online Library
Luteolin is a polyphenolic flavone and has antitumor activity for many cancers. The prostate‐
derived Ets factor (PDEF), a novel epithelium‐specific Ets transcription factor, acts as an …
derived Ets factor (PDEF), a novel epithelium‐specific Ets transcription factor, acts as an …
[HTML][HTML] Non-enzymatic glycoxidation linked with nutrition enhances the tumorigenic capacity of prostate cancer epithelia through AGE mediated activation of RAGE in …
BA Krisanits, P Woods, LM Nogueira, DD Woolfork… - Translational …, 2022 - Elsevier
The molecular implications of food consumption on cancer etiology are poorly defined. The
rate of nutrition associated non-enzymatic glycoxidation, a reaction that occurs between …
rate of nutrition associated non-enzymatic glycoxidation, a reaction that occurs between …